treatment prior study weeks days patients months allowed dose trc 
pregnant patients known included ineligible currently treated time enrollment study 
enrollment prior study time weeks days patients months therapy treatment 
progressive disease rapidly patients evidence therapy time study months treatment 
survival expected months days weeks free greater infection time opinion 
patients disease study prior treatment months defined known score days 
transplant liver post prior days patients months eligible history time 
randomization prior weeks months days therapy treatment date time laboratory 
age time years consent enrollment informed diagnosis study months patients 
screening prior months days weeks hospitalization positive date therapy time 
genders practice birth control willing months time enrollment treatment patients 
entry study prior weeks days months patients time therapy received 
psa doubling time months psadt values patients calculate measurements dt