age years patients patient subject participants subjects months women greater older years old women men patients eighteen japan korea participants age male female years patients time consent subjects informed obtaining aged years patients child parents men women children consent time older age years men women female patients time eighteen subjects men women age years ages greater patients adult status country aged older years male female females time males men adult age years adult patients subjects legal majority amenorrhea appropriate male inclusive years age aged female male donor adult participants men adults years age older old unable infants individuals consent aged older male female years age patients participants subjects consent time