cytotoxic chemotherapy prior days therapy weeks treatment received previous cancer brentuximab vedotin prior treatment bv dose previous bendamustine hypersensitivity received weeks therapy prior chemotherapy treatment nitrosourea dose cytotoxic mitomycin radiation antibody monoclonal weeks prior therapy treatment study received chemotherapy days chemotherapy allowable cancer different prior systemic note study therapy previous treatments prior previous cancer discontinued patients weeks therapies received systemic radiotherapy prior days chemotherapy treatment brain received previous cranial dose