line therapy prior chemotherapy received disease patients treatment systemic second 
therapy prior systemic received chemotherapy patients treatment disease allowed radiation 
therapy prior patients allowed radiation dose weeks days treatment chemotherapy 
radiation therapy prior chemotherapy patients treatment days field gy allowed 
therapies prior number received cancer anti patients allowed systemic limit 
sorafenib hcc prior treatment systemic therapy received intolerance progression patients 
conventional therapy chemotherapy radiation curable weeks patients tumor disease treatment