infection requiring systemic active therapy antibiotics antibiotic intravenous treatment days 
bacterial fungal viral infection active uncontrolled infections systemic requiring antibiotics 
infections active uncontrolled requiring antibiotics systemic illnesses opportunistic patients medical 
pulmonary obstructive disease chronic severe requiring copd antibiotics hospitalization history 
malignancy active years history concurrent treatment second prior requiring patients 
infection active uncontrolled patients ongoing antibiotics eligible presence evidence systemic 
uncontrolled medical severe disease active infection conditions seizures concurrent disorder