monoclonal antibody reaction hypersensitivity severe history antibodies reactions infusion mab 
contraindication contrast mri hypersensitivity known drugs allergy concomitant including gadolinium 
alcohol abuse drug history substance current known dependence active illicit 
tuberculosis tb bacillus active known history previous clinical diagnosis latent 
pembrolizumab excipients hypersensitivity severe known grade epacadostat substance active history 
hamster chinese ovary hypersensitivity recombinant products antibodies known human cell 
hypersensitivity known excipients components history component drugs study formulation excipient 
allergy known hypersensitivity components history study excipients formulations drug formulation 
immediate reaction hypersensitivity idiosyncrasy chemically delayed drugs related dmso excipients 
products hypersensitivity blood known murine investigational tobacco containing study allergy 
metformin taking hypersensitivity reason subjects insulin currently known patients doxycycline 
allergic reactions reaction history anaphylactic severe hypersensitivity humanized proteins antibodies