Patient has a history of non-compliance to medical regimen or inability to grant consent History of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patients with any significant history of non-compliance to medical regimens or with inability to grant a reliable informed consent History of non-compliance to medical regimen or inability to grant consent History of non-adherence to medical regimens or inability to grant consent Patients with any significant history of non-compliance to medical regimens or with inability to grant a reliable informed consent Patient with any significant history of non-compliance to medical regimens or with inability to grant reliable informed consent Patients with any significant history of non-compliance to medical regimens or with inability to grant a reliable informed consent Inability to grant informed consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient with any significant history of non-compliance to medical regimens or with inability to grant reliable informed consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patients with any significant history of non-adherence to medical regimens or with inability to grant reliable informed consent History of non-compliance to medical regimens or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patients with any significant history of non-compliance to medical regimens or with inability to grant reliable informed consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent Patient has a known history of non-compliance to medical regimen or inability to grant consent History of non-compliance to medical regimens or inability to grant consent History of non-compliance to medical regimens or inability to grant consent Patient has a history of non-compliance to medical regimen or inability to grant consent. Patients with any significant history of non-compliance to medical regimens or with inability to grant a reliable informed consent Patient has a history of non-compliance to medical regimen or inability to grant consent