Serum triglyceride level =< mg/dL Part A: Patients must be >= months and < months of age at the time of study enrollment; patients will enroll one dose level behind the dose level at which patients in Part A are enrolling Screen serum erythropoietin level > mIU/mL, TREATMENT INCLUSION: Age to for the first three patients on a dose level; thereafter, if no dose limiting toxicity (DLT), patients aged to can be treated on that dose level Fasting serum triglyceride level =< mg/dL Severely impaired renal or hepatic function (eg, serum creatinine level > mg/dL [. ?mol/L], blood urea nitrogen level > mg/dL [. mmol/L], serum aspartate aminotransferase [AST] level > times the upper limit of normal [ULN], or serum alanine aminotransferase [ALT] level > times ULN). No retropharyngeal nor level IV (or lower) lymphadenopathy (i.e. nodes in level I-III only). Hemoglobin level >= g/dL Patients with serum creatinine level greater than . mg/dL Creatinine level of mg/dL or lower Hemoglobin >= g/dL (may transfuse or use erythropoietin to achieve this level) Serum triglyceride level =< mg/dL within days prior to enrollment Normal serum sodium level without need for supplementation Triglyceride level of no more than mg/dL patients who have a minimum hemoglobin level of (OH) D level less than ng/ml within months of initiation of study; most recent hydroxy D level within last months would be used hemoglobin level lower than g/dL (. mmol/L) or platelet count = . g/dl Hemoglobin level at least . g/dL at Screening visit Patients must have a serum erythropoietin level documented before randomization and =< days before day of study treatment; NOTE: hemoglobin must be < . g/dL at time that serum erythropoietin is drawn Fasting serum triglyceride level =< mg/dL Serum triglyceride level =< mg/dL (=< . mmol/L) Baseline hemoglobin level of > . g/dl Triglyceride level of no more than mg/dL Patients with plasma creatinine level greater than . mg/dL Patients must have documented hemoglobin level of g/dL or higher Be diagnosed with PHPT (inappropriate PTH level in the setting of a high or high-normal serum calcium level greater than or equal to . mg/dL). Serum bilirubin < . x upper limit of normal (ULN) (maximum level based on MD Anderson laboratory ranges is . mg/dL) Anticipating surgery, history of hypothyroidism, profound anemia (hemoglobin level of < g/dL =< days prior to registration), or clinical depression per physician discretion Fibrinogen level < mg/dl Hemoglobin level of at least g/dL (transfusion is allowed to achieve hemoglobin level of at least g/dL). Patients with plasma creatinine level greater than . mg/dL Hemoglobin level of >= g/dL Pregnancy as assessed on baseline blood hCG level Hemoglobin of >= g/dl within weeks of enrollment; if the patient has not had blood drawn for a hemoglobin level in the past two weeks, one will be done to determine the eligibility Patients with plasma creatinine level greater than . mg/dL Hemoglobin of >= g/dl within weeks of enrollment; if the patient has not had blood drawn for a hemoglobin level in the past two weeks, one will be done to determine the eligibility A hemoglobin level < g/dl Have a hemoglobin level of >= g/dL within weeks of enrollment Hemoglobin level of >= g/dL within weeks of enrollment; if the patient has not had blood drawn for a hemoglobin level in the previous two weeks, one will be performed to determine eligibility; patients with a hemoglobin level < g/dL will be referred for treatment of anemia Patients with hypertriglyceridemia with serum triglyceride level >= mg/d (lipid lowering drugs may be used to control level) Patients must have hemoglobin level >= gm/dl (age adjusted if appropriate) provided by the reference laboratory performing the test Patients with a blood creatinine level > . mg/dl within a month of this procedure Diabetic patients with a blood creatinine level > . mg/dl within a month of this procedure Patients with plasma creatinine level greater than . mg/dL