History of myocardial infarction, unstable angina, cardiac or other vascular stenting, angioplasty, or cardiac or vascular surgery within months prior to day of study treatment History of myocardial infarction, cardiac angioplasty or stenting, unstable angina, or other clinically significant cardiac disease within months of enrollment, or have cardiac atrial or cardiac ventricular lymphoma involvement Class III or IV heart failure as defined by the New York Heart Association (NYHA), history of cardiac angioplasty or stenting, documented myocardial infarction or unstable angina within months prior to enrollment, cardiac ejection fraction of < %, or other clinically significant cardiac disease History of any one of the following cardiovascular conditions within the past months: class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease Patients who have experienced untreated and/or uncontrolled cardiovascular conditions and/or have symptomatic cardiac dysfunction (unstable angina, congestive heart failure, myocardial infarction within the previous months; coronary angioplasty, or stenting or bypass grafting within the past months; cardiac ventricular arrhythmias requiring medication; any history of second (nd) or third (rd) degree atrioventricular conduction defects) History of myocardial infarction, cardiac angioplasty or stenting, unstable angina, or other clinically significant cardiac disease within months of enrollment History of myocardial infarction, New York Heart Association (NYHA) class III or IV congestive heart failure, arrhythmia requiring therapy, unstable angina, cardiac or other vascular stenting, angioplasty, or surgery within months prior to the start of study drug History of any one of the following cardiovascular conditions within the past months: class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease History of myocardial infarction, cardiac angioplasty or stenting, unstable angina, or other clinically significant cardiac disease within months of enrollment, or have cardiac atrial or cardiac ventricular lymphoma involvement Arterial or venous thrombi (including stroke), myocardial infarction, admission for unstable angina, cardiac angioplasty, or stenting. History of myocardial infarction, cardiac angioplasty or stenting, unstable angina, New York Heart Association Class II or greater congestive heart failure, or other clinically significant cardiac diseases within months of enrollment History of any one of the following cardiovascular conditions within the past months: class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, or unstable angina; history of other clinically significant cardiac disease that, in the opinion of the PI or designee, is a contraindication to lymphodepleting chemotherapy, JCAR infusion, or durvalumab infusion is also excluded History of myocardial infarction, unstable angina, cardiac or other vascular stenting, angioplasty, or surgery within months prior to day of study treatment; History of any one of the following cardiovascular conditions within the past months: Class III or IV heart failure as defined by the New York Heart Association, cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease History of any of the following cardiovascular conditions within the past months:\r\n* Class III or IV congestive heart failure as defined by the New York Heart Association Criteria\r\n* Cardiac angioplasty or stenting\r\n* Myocardial infarction\r\n* Unstable angina\r\n* Symptomatic peripheral vascular disease or other clinically significant cardiac disease Patient must have no history of myocardial infarction, hospital admission for unstable angina, cardiac angioplasty or stenting within months of randomization Cardiac angioplasty or stenting History of any one or more of the following cardiac conditions within the past months: Cardiac angioplasty or stenting; Myocardial infarction; Unstable angina; History of Class III or IV congestive heart failure according to New York Heart Association classification History of myocardial infarction, unstable angina, cardiac or other vascular stenting, angioplasty, or cardiac surgery =< months prior to registration History of myocardial infarction, cardiac angioplasty or stenting, unstable angina, or other clinically significant cardiac disease within months of enrollment History of myocardial infarction, unstable angina, cardiac or other vascular stenting, angioplasty, or surgery =< months prior to randomization The participant has unstable angina pectoris, angioplasty, cardiac stenting, or myocardial infarction within months of randomization. Cardiac angioplasty or stenting History of any one of the following cardiovascular conditions within the past months: Class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease Uncontrolled illnesses including symptomatic congestive heart failure (class III or IV as per New York Heart Association functional classification system), unstable angina pectoris, cardiac arrhythmia requiring therapy, myocardial infarction within the past months, cardiac angioplasty or stenting within last months, arterial or venous thrombi (including cerebrovascular accident), or active infection History of any one of the following cardiovascular conditions within the past months: Class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease History of significant cardiovascular disease (i.e. NYHA class congestive heart failure; myocardial infarction with the past months; unstable angina; coronary angioplasty with the past months; uncontrolled atrial or ventricular cardiac arrhythmias) History of any one or more of the following cardiovascular conditions within the past months:\r\n* Cardiac angioplasty or stenting\r\n* Myocardial infarction\r\n* Unstable angina\r\n* Symptomatic peripheral vascular disease\r\n* Class III or IV congestive heart failure, as defined by the New York Heart Association (NYHA) History of clinically significant cardiovascular condition with the past months (e.g. angioplasty or stenting, myocardial infarction, unstable angina, bypass surgery, symptomatic peripheral arterial disease [PAD], class III or IV congestive heart failure) Significant cardiac conditions (myocardial infarction [heart attack], unstable angina, coronary angioplasty, cardiac bypass) or serious arrhythmia within months History of any one of the following cardiovascular conditions within the past months: Class III or IV heart failure as defined by the New York Heart Association (NYHA), cardiac angioplasty or stenting, myocardial infarction, unstable angina, or other clinically significant cardiac disease