Signs or symptoms of infection within weeks prior to randomization Patients must not have clinical signs or symptoms of active tuberculosis infection Signs or symptoms of infection within days prior to randomization Signs or symptoms of infection within weeks before initiation of study treatment Signs or symptoms of infection within weeks prior to first day of study Signs or symptoms of infection within weeks prior to start of study treatment. Signs or symptoms of infection within weeks prior to first day of study treatment Signs or symptoms of infection within weeks prior to the first study treatment Signs or symptoms of infection within weeks prior to study treatment Patients who have signs or symptoms of infection within weeks before initiation of study treatment Signs or symptoms of infection =< weeks prior to registration Signs or symptoms of infection within weeks prior to week , day Signs or symptoms of infection within weeks prior to first dosing. Signs/symptoms of infection, or use of antibiotics within weeks of study drug Signs or symptoms of severe infection (sepsis) within weeks prior to treatment start Signs or symptoms of infection within weeks prior to the first dose of study treatment Treatment with antibiotics for proven infection within week prior to study entry or signs and symptoms consistent with an active infection or fever > . C. Signs or symptoms of significant infection within weeks prior to Day No signs or symptoms of BRONJ