Within days of registration: Aspartate aminotransferase (AST) =< . x upper limits of normal (ULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) < . x upper limits of normal (ULN) Serum transaminases (aspartate aminotransferase [AST] and alanine aminotransferase [ALT]) less than three times the upper limits of normal (ULN) Aspartate aminotransferase (AST) ? . x upper limits of normal Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) up to . x upper limits of normal (ULN).\r\n* Patients known to have Gilberts disease may be eligible with AST and ALT up to x ULN. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . x upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) < . x upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< times the institutional upper limits of normal. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< X the upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) < . x upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< times the institutional upper limits of normal Patients must have an alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . times the institutional upper limits of normal If the research participant is to undergo leukapheresis, he/she must have alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . times the institutional upper limits of normal\r\n* Note: in the event a patient has elevated levels of liver enzymes possibly related to underlying disease, the patient will still be considered eligible Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . x the upper limits of normal Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x upper limits of normal Aspartate aminotransferase (AST)/alanine aminotransferase (ALT ) < . x the upper limits of institutional normal (=< x ULN for patients with liver involvement of leukemia) Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< x upper limits of normal Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than . times the upper limits of normal within days prior to starting treatment in the absence of liver metastasis; in the presence of liver metastasis serum AST and ALT less than or equal to . times the upper limits of normal within days prior to starting treatment Adequate hepatocellular function: aspartate aminotransferase (AST) and alanine transaminase (ALT) ? x upper limit of normal within institutional limits; bilirubin ? . mg/dl HPV-ASSOCIATED OROPHARYNX SQUAMOUS CELL CARCINOMA: Aspartate aminotransferase (AST/ SGOT) and alanine aminotransferase (ALT/ SGPT) < x the upper limits of normal (ULN) Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) < . x the upper limits of institutional normal (=< x ULN for patients with suspected liver involvement of leukemia) Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) < . x upper limits of normal Performed within days prior to study: Alanine aminotransferase (ALT) < times the upper limits of the institutional normal Performed within days prior to study: Aspartate aminotransferase (AST) < times the upper limits of the institutional normal Liver disease: alanine aminotransferase (ALT) or aspartate aminotransferase (AST) greater than times the upper limits of normal, unless determined to be a result of the primary hematologic malignancy Creatinine within normal institutional limits OR creatinine clearance > mL/min/. m^ for subjects with above normal aspartate aminotransferase (AST) and alanine aminotransferase (ALT) with alkaline phosphatase within < . times upper limit of normal Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x upper limits of normal (ULN) Alanine aminotransferase (ALT), aspartate aminotransferase (AST) =< x institutional upper limits of normal (IULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x upper limits of normal (ULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x upper limits of normal Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< . times the upper limits of normal Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) >= x laboratory upper normal limits Aspartate aminotransferase (AST) =< . x upper limits of normal (ULN); for patients with liver metastasis: =< x upper limits of normal (ULN) Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< times above the upper limits of the institutional norm; ALT, AST can be < times upper limits of normal if patients have hepatic involvement Hepatic function: serum albumin >. g/dL; aspartate aminotransferase (AST/SGOT) and alanine aminotransferase (ALT/SGPT) x upper limits of normal (ULN) Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than . times the upper limits of normal; note: if hepatic function is abnormal, the decision to initiate temozolomide treatment should carefully consider the benefits and risks for the individual patient Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) must each be =< . x the upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< times above the upper limits of the institutional normal (norm) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< x upper limits of normal Aspartate aminotransferase (AST) =< x institutional upper limits of normal (ULN) Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) below the institutional upper limits of normal Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< x upper limits of normal Aspartate aminotransferase (AST) + alanine aminotransferase (ALT) > upper limits of normal value Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< . x upper limits of normal Aspartate aminotransferase (AST) =< x the upper limits of normal Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< . X normal institutional limits Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than . times the upper limits of normal Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) within normal limits Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< x the upper limits of normal Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x upper limits of normal Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) =< . x upper limits of normal (ULN) Aspartate aminotransferase (AST) =< . x upper limits of normal Liver enzymes (aspartate aminotransferase [AST] and alanine aminotransferase [ALT]) >= . times the upper limits of normal (ULN) days prior to study enrollment Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ? . times upper limits of normal prior to chemotherapy Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) >= x of the upper limits of normal Patients with liver dysfunction: total bilirubin > . mg/dl; albumin < . mg/dl; alanine aminotransferase (ALT), aspartate aminotransferase (AST) > times upper limits of normal Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) > . x ULN (institutional upper limits of normal); > x ULN if liver metastasis Aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) greater than . x upper limits of normal Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) within normal institutional limits Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) within normal limits