Diagnosis of amyloidosis Subjects with known or suspected amyloidosis of any organ Pts with primary systemic amyloidosis Patients with multi-organ involvement by amyloidosis or evidence of amyloidosis-related organ dysfunction COHORT B: biopsy proven light chain amyloidosis with organ involvement requiring therapy Known amyloidosis (MM patients) Known or suspected amyloidosis Patients with primary systemic amyloidosis Primary amyloidosis Amyloidosis Systemic amyloid light chain amyloidosis Patients with non-secretory MM or known primary amyloidosis are not eligible Diagnosis of amyloidosis Primary amyloidosis Patients with non-secretory MM or known amyloidosis are not eligible Amyloidosis History of or current amyloidosis Subjects with known or likely systemic amyloidosis No primary amyloidosis Amyloidosis Subjects with known or likely systemic amyloidosis Subjects with known or suspected amyloidosis of any organ Secondary or familial amyloidosis; Primary amyloidosis Any form of secondary / familial amyloidosis Amyloidosis Primary amyloidosis (amyloidosis associated with multiple myeloma is allowed). Presence of primary (light chain) amyloidosis. Primary amyloidosis (amyloidosis associated with multiple myeloma is allowed). Patients with known amyloidosis Patients with known amyloidosis Known amyloidosis Patients with primary systemic amyloidosis. Patients with known amyloidosis. Documented active systemic amyloid light chain amyloidosis. Amyloidosis Documented systemic light chain amyloidosis.