No history of congenital prolonged corrected QT (QTc) syndrome, New York Heart Association (NYHA) class III or IV congestive heart failure (CHF)
New York Heart Association (NYHA) class II, NYHA class III, or IV congestive heart failure (any symptomatic heart failure)
Congestive heart failure (CHF) New York (NY) Heart Association class III or IV
New York Heart Association (NYHA) class III or IV congestive heart failure, ventricular arrhythmias or uncontrolled blood pressure
New York Heart Association Class II-IV congestive heart failure
Patients with chronic kidney disease (glomerular filtration rate [GFR] < ), uncontrolled hypertension, congestive heart failure, pre-existing bone marrow dysfunction, or cytopenias\r\n* Congestive heart failure (CHF): New York Heart Association (NYHA) class II-IV at the time of screening
Patients with any class of New York Heart Association (NYHA) congestive heart failure (CHF) or heart failure with preserved ejection fraction (HFPEF)
Symptomatic congestive heart failure (CHF), New York Heart Association (NYHA) Class III or IV heart failure or other clinical signs of severe cardiac dysfunction
Current congestive heart failure (New York Heart Association Class II, III or IV)
New York Heart Association heart failure class >= 
Participants with a history of congestive heart failure (New York Heart Association [NYHA] class II, III or IV) are excluded
Symptomatic congestive heart failure of New York heart Association Class III or IV
New York Heart Association (NYHA) class III or IV congestive heart failure.
New York Heart Association class III or IV heart failure
New York Heart Association Class II, III, or IV congestive heart failure
New York Heart Association Class III or IV heart failure
Participants with a history of congestive heart failure or New York Heart Association (NYHA) class III or IV functional status are excluded
Congestive heart failure of New York Heart Association class III/IV,
New York Heart Association (NYHA) Class III or IV heart failure
New York Heart Association class III or IV heart failure
Heart failure, class IV by New York Heart Association criteria
Subjects with New York Heart Association (NYHA) class III or IV heart failure.
New York Heart Association class III or IV heart failure
Symptomatic congestive heart failure (New York Heart Association class >= ) within the  months prior to study drug administration
New York Heart Association Class III to IV heart failure.
Absence of New York Heart Association (NYHA) class II, III, or IV congestive heart failure
Other clinically significant heart disease (New York Heart Association [NYHA] class  heart failure, uncontrolled hypertension)
Congestive heart failure (CHF): New York Heart Association (NYHA) Class III (moderate) or Class IV (severe) at the time of screening
New York Heart Association Class III or IV heart failure.
Uncontrolled cardiac angina or symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV)
History of congestive heart failure New York Heart Association (NYHA) class III or IV or uncontrolled hypertension at screening.
New York Heart Association (NYHA) class IV heart failure
Current evidence of active and uncontrolled infection, New York Heart Association (NYHA) class III-IV congestive heart failure (CHF), documented Childs class B-C cirrhosis, active pancreatitis or uncontrolled medical disease which in the opinion of the investigator could compromise assessment of efficacy
Congestive heart failure > New York Heart Association (NYHA) class 
Congestive heart failure > New York Heart Association (NYHA) class 
congestive heart failure (New York Heart Association class III to IV)
Subject has severe cardiovascular disease, i.e. arrhythmias, requiring chronic treatment, congestive heart failure (New York Heart Association [NYHA] class III or IV) or symptomatic ischemic heart disease
Active congestive heart failure (New York Heart Association [NYHA] class III to IV), symptomatic ischemia, or conduction abnormalities uncontrolled by conventional intervention
Congestive heart failure (New York Heart Association class III or IV)
New York Heart Association class III/IV heart failure
New York Heart Association class - heart failure
Class III or IV congestive heart failure, as defined by the New York Heart Association (NYHA)
New York Heart Association class III or greater congestive heart failure
Patients with New York Heart Association (NYHA) class III or IV heart failure will be excluded
Congestive heart failure New York Heart Association (NYHA) class  or 
Congestive heart failure (New York Heart Association [NYHA] II, III, IV)
Congestive heart failure (CHF) NYHA (New York Heart Association) > Class 
History of congestive heart failure of Class II-IV New York Heart Association (NYHA) criteria, or serious cardiac arrhythmia requiring treatment (except atrial fibrillation, paroxysmal supraventricular tachycardia).
Patients with congestive heart failure, Class III or IV, by New York Heart Association (NYHA) criteria.
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions
Patients with NYHA (New York Heart Association) class III or IV heart failure or history of a prior myocardial infarction (MI) within the last five years prior to enrollment in the study
New York Heart Association (NYHA) stage III/IV congestive heart failure, arrhythmias not adequately controlled.
History of symptomatic congestive heart failure (New York Heart Association [NYHA] Class III or IV).
New York Heart Association (NYHA) class  or  congestive heart failure (CHF) symptoms
Congestive heart failure of any severity (New York Heart Association [NYHA] class I-IV)
Heart failure that meets New York Heart Association (NYHA) class III and IV definitions
Symptomatic congestive heart failure of New York Heart Association Class III or IV.
Grade III/IV congestive heart failure, as defined by New York Heart Association (NYHA) criteria, or myocardial infarction within  months
Current congestive heart failure (New York Heart Association class II-IV).
For Cohort B:Has symptomatic congestive heart failure (New York Heart Association Class III or IV heart disease)
History of class III or IV congestive heart failure, as defined by the New York Heart Association Classification of Congestive Heart Failure
Congestive heart failure (New York Heart Association class III to IV)
Class III or IV congestive heart failure per New York Heart Association
New York Heart Association (NYHA) Class III or IV congestive heart failure;
documented New York Heart Association (NYHA) Class III or IV congestive heart failure;
New York Heart Association (NYHA) class III or IV congestive heart failure
New York Heart Association (NYHA) class IV congestive heart failure
New York Heart Association (NYHA) class III or IV congestive heart failure
known autoimmune disease, known bleeding diathesis, history of congestive heart failure New York Heart Association (NYHA) class III or IV;
have congestive heart failure or poorly controlled cardiac arrhythmia per New York Heart Association Class II-IV heart disease
New York Heart Association Class III or IV heart failure;
Have symptomatic congestive heart failure (New York Heart Association II-IV) or symptomatic or poorly controlled cardiac arrhythmia.
Patients with class III or class IV heart failure by New York Heart Association, those with unstable angina, and those with uncontrolled arrhythmia are not eligible
Subject has congestive heart failure classified as New York Heart Association Class IV.
The participant has symptomatic congestive heart failure (New York Heart Association II-IV) or symptomatic or poorly controlled cardiac arrhythmia.
Congestive heart failure (CHF): New York Heart Association (NYHA) class III (moderate) or class IV (severe) at the time of screening
Congestive heart failure > New York Heart Association (NYHA) class 
History of Class III or IV congestive heart failure, as defined by the New York Heart Association Classification of Congestive Heart Failure
No symptomatic congestive heart failure (New York Heart Association class II, III, or IV) within  months prior to registration
Symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV), or unstable angina pectoris
Current New York Heart Association (NYHA) class II, III, or IV congestive heart failure or symptomatic heart failure within  days prior to the start of study drugs
Symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV), or unstable angina pectoris
Patients with myocardial impairment of any cause (e.g. cardiomyopathy, ischemic heart disease, significant valvular dysfunction, hypertensive heart disease, and congestive heart failure) resulting in heart failure by New York Heart Association Criteria (Class III or IV staging)
Active congestive heart failure (New York Heart Association [NYHA] class II-IV)
Class III or IV congestive heart failure, as defined by the New York Heart Association (NYHA)
Symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV), unstable angina pectoris or congenital long QT syndrome
New York Heart Association (NYHA) class II, NYHA class III, or IV congestive heart failure (any symptomatic heart failure)
Class III or IV congestive heart failure, as defined by the New York Heart Association (NYHA)
History of uncontrolled congestive heart failure defined as New York Heart Association (NYHA) class III or greater
New York Heart Association Class III or IV heart failure
Class II, III or IV congestive heart failure, as defined by the New York Heart Association (NYHA)
Active congestive heart failure (New York Heart Association [NYHA] class III to IV), symptomatic ischemia, or conduction abnormalities uncontrolled by conventional intervention
Patients with congestive heart failure, class III or IV, by the New York Heart Association (NYHA) criteria
Uncontrolled intercurrent illness including, but not limited to, the following:\r\n* Active infection\r\n* Congestive heart-failure (New York Heart Association [NYHA] grade III or IV)
Uncontrolled malignant arrhythmias or clinical evidence of congestive heart failure (New York class IV)
Subject currently has Class  or  New York Heart Association congestive heart failure.
Clinical evidence of significant congestive heart failure (CHF) (New York Heart Association [NYHA] Class III or IV)
Subject currently has Class III or IV New York Heart Association congestive heart failure.
Patients with New York Heart Association (NYHA) heart failure class > 
-  Subject currently has Class  or  New York Heart Association congestive heart failure.
Symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV)
Class II-IV congestive heart failure, as defined by the New York Heart Association
Any uncontrolled congestive heart failure New York Heart Association class III or IV
Uncontrolled hypertension or congestive heart failure Class III/IV per the New York Heart Association's Heart Failure Guidelines
Patients with New York Heart Association (NYHA) class  or  congestive heart failure
Class II-IV New York Heart Association (NYHA) congestive heart failure
Class III or IV congestive heart failure by New York Heart Association
Have congestive heart failure (CHF) New York Heart Association class ? or symptomatic or poorly controlled cardiac arrhythmia.
Subject has current symptomatic heart failure or a history of congestive heart failure New York Heart Association (NYHA) class  or 
Unstable angina, significant cardiac arrhythmia, or New York Heart Association (NYHA) class III or IV congestive heart failure
Current congestive heart failure (New York Heart Association Class II-IV).
Patients with history of and/or current evidence of myocardial impairment (e.g. cardiomyopathy, ischemic heart disease, significant valvular dysfunction, hypertensive heart disease, and congestive heart failure) resulting in heart failure by New York Heart Association Criteria (Class III or IV staging)
Congestive heart failure or prior history of New York Heart Association (NYHA) class III/ IV cardiac disease;
Congestive heart failure New York Heart Association Class III or IV, or Class II with a recent decompensation requiring hospitalization within  weeks before screening.
History of class III or IV congestive heart failure, as defined by the New York Heart Association
Symptomatic congestive heart failure of New York Heart Association Class III or IV
Congestive heart failure of New York Heart Association (NYHA) class III or higher severity at study entry
New York Heart Association class III or IV heart failure
Patients with a history of congestive heart failure of any New York Heart Association class
Patients with New York Heart Association (NYHA) class II-IV heart failure
The participant has current clinically-relevant coronary artery disease (New York Heart Association III or IV) or uncontrolled congestive heart failure.
Patients with history of and/or current evidence of myocardial impairment (e.g. cardiomyopathy,ischemic heart disease, significant valvular dysfunction, hypertensive heart disease, and congestive heart failure) resulting in heart failure by New York Heart Association Criteria (Class III or IV staging)
Subject currently has Class  or  New York Heart Association congestive heart failure.
History of symptomatic congestive heart failure of any New York Heart Association class or serious cardiac arrhythmia requiring treatment
History of congestive heart failure (CHF) New York Heart Association (NYHA) class  or ;
Uncontrolled heart failure as defined by New York Heart Association (NYHA) class  or 
Clinically significant cardiac disease defined by congestive heart failure New York Heart Association (NYHA) Class  or Class .
Current or history of New York Heart Association Class III or IV heart failure.
New York Heart Association class III or IV heart failure
History of New York Heart Association Class  or  heart failure;
Uncontrolled cardiac angina or symptomatic congestive heart failure (New York Heart Association [NYHA] class III or IV)
Congestive Heart Failure NY Heart Association class III or IV
New York Heart Association (NYHA) class IV congestive heart failure;
Symptomatic congestive heart failure of New York heart Association Class III or IV
New York Heart Association (NYHA) class III and IV congestive heart failure
Congestive heart failure (New York Heart Association [NYHA] class III or IV)
New York Heart Association (NYHA) class III and IV congestive heart failure
Patients with uncontrolled congestive heart failure (New York Heart Association [NYHA] Class IV)
Current or history of New York Heart Association Class III or IV heart failure
Congestive heart failure (New York Heart Class III or IV).