Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Participants who are involved in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Participants with involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in study planning and conduct (i.e., Hansoh staff or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both investigator staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to AstraZeneca and/or Sarah Cannon Development Innovations staff and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at MD Anderson). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site), previous enrollment in the present study. Involvement in the planning and/or conduct of the study (applies to staff at the study site) or previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) or previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) or previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrolment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrolment or randomization in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment or randomization in the present study Patients who are involved in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment or randomization in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). safety of study staff Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and staff at University of Iowa Hospitals and Clinics [UIHC]) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) safety of study staff Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca, contract research organization [CRO] staff, and/or staff at the central processing unit [CPU]) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site); previous enrollment in the present study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff, its agents and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). safety of study staff Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site). Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applied to both AstraZeneca staff and/or staff at the study site); previous enrollment in the previous study Involvement in the planning and/or conduct of the study (applies to both AstraZeneca Representative staff and/or staff at the study site); Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site) Involvement in the planning and conduct of the study (applies to both Astra Zeneca staff and staff at the study site) Involvement in the planning and/or conduct of the study (applies to both AstraZeneca, Contract Research Organization [CRO] staff, and/or staff at the CPU)