Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Ability to understand a written informed consent document, and the willingness to sign it; assent will be obtained when appropriate based on the subjects age Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document. Ability to understand a written informed consent document, and the willingness to sign it. Assent will be obtained when appropriate based on the subjects age. Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Ability to understand and the willingness to sign a written informed consent document; only subjects who have capacity to consent will be enrolled in the study Subjects must have the ability to understand and the willingness to sign a written informed consent document. Subjects must have the ability to understand and the willingness to sign a written informed consent document. Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document PHASE I: Subjects must have the ability to understand and the willingness to sign a written informed consent document PHASE II: Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document TUMOR BIOPSY SEQUENCING: Ability to understand and the willingness to sign a written informed consent document (subjects with impaired decision-making capacity are not eligible) Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects should have the ability to understand and the willingness to give verbal and sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document. Subjects must have the ability to understand and the willingness to sign a written informed consent document, or assent document Subjects must have the ability to understand and the willingness to sign a written informed consent document All subjects must have the ability to understand and the willingness to sign a written informed consent document Ability to understand and the willingness to sign a written informed consent document; subjects must be willing to adhere to dose and visit schedules Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and the willingness to sign a written informed consent document Subjects must have the ability to understand and willingness to sign a written informed consent document. Subjects will have the ability to understand, and the willingness to sign a written informed consent document