Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds. Patients must have no known allergies to exemestane, entinostat, or medications that have a benzamide structure (e.g., tiapride, remoxipride, clebropride) Patients with known and documented allergies to any of the penicillins, cephalosporins, or beta-lactamase inhibitors Subjects with known allergies, hypersensitivity, or intolerance to niraparib or its excipients Known allergies to medical adhesives or hydrogel Known allergies to medical adhesives or hydrogel History of allergies to any active or inactive ingredients of atezolizumab. Participants with known allergies, hypersensitivity, or intolerance to ibrutinib or its excipients (refer to Investigator's Brochure) Patients with known or suspected allergies to any component of the vaccine. Known allergies to medical adhesives or hydrogel Patients with known contrast allergies requiring pre-medication with steroids Known allergies, hypersensitivity or intolerance to apalutamide, abiraterone acetate, prednisone, or GNRH agonist or GNRH antagonist Known allergies, hypersensitivity, or intolerance to erdafitinib or its excipients Subjects with three or more drug allergies from separate drug classes Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds History of multiple drug allergies or intolerance to subcutaneous injections Subjects with three or more drug allergies from separate drug classes Allergies, hypersensitivity, or intolerance to prednisone, LHRH analog or excipients of prednisone LHRH analog, abiraterone acetate and apalutamide. Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds Subject has known severe allergies, hypersensitivity, or intolerance to monoclonal antibodies or human proteins, or their excipients (refer to the latest version of the Investigator Brochure), or known sensitivity to mammalian-derived products Known allergies, hypersensitivity, or intolerance to corticosteroids, monoclonal antibodies or human proteins, or their excipients (refer to respective package inserts or investigator's brochure), or known sensitivity to mammalian-derived products Allergies to any vaccine, that after discussion with Immunovaccine, are serious enough to warrant exclusion from this study Have known allergies, hypersensitivity, or intolerance to ARN- (apalutamide) or its excipients Prior use of niclosamide or allergies to niclosamide Allergies to Lidocaine or Novocain Allergies to imaging dyes Documented penicillin or cephalosporin allergies Subjects with any underlying conditions, which would contraindicate therapy with, study treatment (or allergies to reagents used in this study) Known allergies to any of the components of the investigational treatment regimen or required ancillary treatments Patients with allergies to any component of the vaccine will be excluded from the protocol Subjects must not have allergies to any compounds similar to CDB- Have known allergies, hypersensitivity, or intolerance to abiraterone acetate, apalutamide or prednisone or their excipients Known allergies, hypersensitivity, or intolerance to the IP or its excipients Allergies, hypersensitivity, or intolerance to niraparib or the corresponding excipients Allergies to lidocaine or marcaine Allergies to imaging dyes Known history of allergies or sensitivities to gentamicin. Patients with allergies to isosulfan blue or technetium, which would preclude sentinel node mapping Subject has known allergies, hypersensitivity, or intolerance to monoclonal antibodies or human proteins, or their excipients Antibiotic allergies that would preclude treatment for a C. novyi-NT infection Subject has known allergies, hypersensitivity, or intolerance to boron or mannitol, corticosteroids, monoclonal antibodies or human proteins, or their excipients (refer to respective package inserts or Investigator's Brochure), or known sensitivity to mammalian-derived products Participants with known or suspected allergies to any component of the vaccine Known allergies to clofarabine, melphalan, sirolimus or tacrolimus Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds. Known allergies, hypersensitivity, or intolerance to Doxil, dexamethasone, or their excipients Known allergies, hypersensitivity, or intolerance to talacotuzumab and daratumumab or their excipients Allergies or hypersensitivities to monoclonal antibodies, BMS- or related compounds, including fucosyl-GM vaccine and Nivolumab Subjects with any known severe allergies (e.g. anaphylaxis) to any active or inactive ingredients in the study drugs. Participant has known allergies, hypersensitivity, or intolerance to imetelstat or its excipients Known allergies, hypersensitivity, or intolerance to any form of heparin or azacitidine No eating disorders, food allergies or intolerances Have known allergies, hypersensitivity, or intolerance to AA or prednisone or their excipients Have known allergies, hypersensitivity, or intolerance to abiraterone acetate or prednisone or their excipients Have known allergies, hypersensitivity, or intolerance to enzalutamide or their excipients Have known allergies, hypersensitivity, or intolerance to abiraterone acetate or prednisone or their excipients Any prior allergies to curcumin or turmeric Known allergies to any of the components of the investigational treatment regimen or required ancillary treatments Any history of allergies to grapes or grape seed Have known allergies, hypersensitivity, or intolerance to abiraterone acetate or prednisone or their excipients Known allergies, hypersensitivity or intolerance to abiraterone acetate, prednisone or degarelix Subjects with any underlying conditions which would contraindicate therapy with study treatment (or allergies to reagents) Subject has any underlying conditions, which would contraindicate therapy with study treatment (or allergies to reagents used in this study) Known allergies, hypersensitivity, or intolerance to TRC or its excipients. Have known allergies, hypersensitivity, or intolerance to docetaxel or dexamethasone or their excipients Antibiotic allergies that would preclude treatment for a C. novyi-NT infection. Allergies to excipients in the study drug. Hypersensitivities, allergies or contraindications to study medications; intolerance of medical tape or sticking plaster. Have known allergies, hypersensitivity, or intolerance to enzalutamide or niclosamide or their excipients Known allergies, hypersensitivity or intolerance to prednisone or excipients of abiraterone acetate or enzalutamide. History of hypersensitivity to docetaxel or polysorbate . Have known allergies or hypersensitivity to abiraterone acetate or prednisone or their excipients Allergies to temozolomide, dacarbazine, IgG containing agents Patients with known allergies, hypersensitivity, or intolerance to abiraterone acetate or prednisone or their excipients Allergies to any component of the vaccine Known unmanageable allergies, hypersensitivity, intolerance to monoclonal antibodies, to murine, chimeric, human proteins or their excipients Known allergies, hypersensitivity, or intolerance to trabectedin, dacarbazine, dexamethasone, or their excipients Known allergies, hypersensitivity, or intolerance to dacarbazine does not apply Allergies to eggs, lecithin or soy products. No allergies to and not currently using varenicline Subjects with allergies to any supplements. Patients with allergies to any of the ingredients in the nutritional supplement Known allergies or intolerance to cisplatin and similar platinum-containing compounds Allergic history, including anaphylaxis or severe allergies to products in study serum or placebo Hypersensitivity to any tetracycline, or a history of other allergies or drug reactions that in the treating physician's judgment make the patient inappropriate for this study Has known allergies or intolerance to brilacidin, cisplatin or carboplatin Patients will be excluded from the trial if they have had a history of allergies or intolerance to fructooligosaccharides or the components of FOS including fructose and glucose Known allergies or intolerance to cisplatin and similar platinum-containing compounds Known allergies, hypersensitivity, or intolerance to any of the study medications. All patients who are have known allergies or are sensitive to silver and acrylic adhesives Allergies to multiple food items or nutritional supplements Known allergies, hypersensitivity, or intolerance to corticosteroids, monoclonal antibodies, hyaluronidase, or other human proteins, or their excipients, or known sensitivity to mammalian-derived products History of food allergies and/or major dietary restrictions Subjects should not have known allergies to cruciferous vegetables No known allergies to tree nuts (i.e. almonds) Subjects with three or more drug allergies from separate drug classes Subject has known allergies, hypersensitivity, or intolerance to monoclonal antibodies or human proteins, or their excipients (refer to respective package inserts or investigator's brochure) Subjects with three or more drug allergies from separate drug classes No known allergies to contrast material No known allergies to contrast material Known allergies to contrast material History of allergies to iodides Subjects with a history of iodide allergies Subjects with three or more drug allergies from separate drug classes Subjects with three or more drug allergies from separate drug classes Allergies to study medications, such as, lidocaine, Versed, or Cetacaine Allergies and Adverse Drug Reaction a. Subjects with known hypersensitivity to excipients of Dasatinib tablets