Must be obtained within days prior to registration for protocol therapy: International normalized ratio (INR) or prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy; if subject on anticoagulant therapy, PT or PTT must within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation:\r\nInternational normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or Prothrombin Time (PT) ?. ULN unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (within days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT/INR/ partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants obtained within days prior to registration Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (up to days before treatment initiation) International normalized ratio (INR)/ prothrombin time (PT) =< . x institutional ULN unless subject is receiving anticoagulant therapy as long as PT or INR is within therapeutic range of intended use of anticoagulants Within days of treatment initiation:\r\nInternational normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR)/prothrombin time (PT) =< . times ULN unless participant is receiving anticoagulant therapy, as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation COHORT : International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation COHORT : International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants within days of treatment initiation SAFETY RUN-IN: Within days of registration: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants RANDOMIZED PHASE II CLINICAL TRIAL: Within days of registration: International normalized ratio (INR) or PT =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulant. INR or PT ? . x ULN unless subject is receiving anticoagulant therapy as long as PT and PTT are within therapeutic range of intended use of anticoagulants. Within (except as noted) days of planned treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN, unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR), activated partial thromboplastin time (aPTT) or prothrombin time (PT) =< . times the ULN unless subject is receiving anticoagulation therapy as long as PT or aPTT are within therapeutic range of intended use of anticoagulant International normalized ratio (INR) or prothrombin time (PT) < . x ULN unless subject is receiving anticoagulation therapy as long as PT or INR is within therapeutic range of intended use of anticoagulant within days of treatment initiation and must be independent of hematopoietic growth factor support International normalized ratio or prothrombin time =< . X ULN unless patient is receiving anticoagulant therapy as long as prothrombin time (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants. International normalized ratio (INR) or prothrombin rime (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation Within days of treatment registration: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) < . times the upper limit of normal unless subject is receiving anticoagulant therapy, as long as PT or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) < . times the upper limit of normal unless subject is receiving anticoagulant therapy, as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) < . times the upper limit of normal unless subject is receiving anticoagulant therapy, as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants or patient has disseminated intravascular coagulation deemed by investigator to be due to leukemia, performed within days of D of treatment under LCCC International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as prothrombin time (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (performed within days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . X institutional ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, performed within days of study registration International normalized ratio (INR) =< . x IULN unless patient is receiving anticoagulant therapy as long as INR or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x IULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) =< . x IULN unless patient is receiving anticoagulant therapy as long as INR or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Performed within business days of treatment initiation with the exception of beta- HCG ( hours), if applicable: International normalized ratio (INR) or prothrombin time (PT) =<. X ULN unless subject is receiving anticoagulant therapy as long as PT or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants. Within days prior to the start of study treatment: International normalized ratio (INR) OR prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . x ULN unless participant is receiving anticoagulant therapy as long as PT or aPTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, should be performed within days of treatment initiation If not receiving anticoagulants: international normalized ratio (INR) OR prothrombin (PT) =< . x ULN, performed within days prior to day of protocol therapy\r\n* If on anticoagulant therapy: PT must be within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio or prothrombin time =< . X ULN unless subject is receiving anticoagulant therapy as long as prothrombin time (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation Performed within days of treatment initiation: international normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Should be performed within days of treatment initiation: international normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of cycle day : International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving\r\nanticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants (performed within days of treatment initiation) Within days prior to the start of study treatment: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants. International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin rime (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Coagulation international normalized ratio (INR) or prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants. To be performed within days of treatment initiation: international normalized ratio (INR) or prothrombin time (PT) ? . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT is within therapeutic range of intended use of anticoagulants within days of treatment initiation Prothrombin time (PT)/international normalized ratio (INR) and partial thromboplastin time (PTT) =< . x institutional unless the subject is on anticoagulant therapy (if the subject is receiving anticoagulant therapy, PT, and activated partial thromboplastin time [aPTT] must be within therapeutic range of intended use of anticoagulants) Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants. Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =<. X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range on intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants. Within days of registration: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants Obtained =< days prior to registration: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days prior to on-study date: International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or activated partial thromboplastin time (aPTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) =< . x ULN unless subject is receiving anticoagulant therapy as long as prothrombin time (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use on anticoagulant Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants AND activated partial thromboplastin time (aPTT) =< . x ULN unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or Prothrombin Time (PT) ?. times the ULN and Activated Partial Thromboplastin Time (aPTT) ?. times the ULN. Note: If patient is receiving anticoagulant therapy, then PT or PTT must be within therapeutic range of intended use of anticoagulants; International normalized ratio (INR) or prothrombin time (PT) =<. x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, performed within days of protocol registration Within days prior to registration for protocol therapy: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy; in the case of anticoagulants, PT/INR/partial thromboplastin time (PTT) must be within therapeutic range of intended use of anticoagulants Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Determined within weeks of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X institutional ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of registration To be performed within business days prior to day : If not receiving anticoagulants: international normalization ratio (INR) OR prothrombin (PT) =< . x ULN; if on anticoagulant therapy: PT must be within therapeutic range of intended use of anticoagulants Within days prior to planned start of treatment: If not receiving anticoagulants: international normalized ratio (INR) AND prothrombin (PT) =< . x ULN\r\n* If on anticoagulant therapy: PT must be within therapeutic range of intended used of anticoagulants Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulant (performed within days of registration) International Normalized Ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy, in which case, the PT/INR should be within therapeutic range for intended use, performed within days of treatment initiation International normalized ratio (INR) and/or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (within - days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, during screening and on cycle , day International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (performed within days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or Prothrombin Time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT): =< . unless participant is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Completed within days of SBRT treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =<. x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants If not receiving anticoagulants: international normalized ratio (INR) OR prothrombin (PT) =< . x ULN; if on anticoagulant therapy: PT must be within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . X ULN within days of treatment initiation unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days prior to registration International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Performed days prior to study registration up to the first dose of study drug: international normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy; if subject receiving anticoagulants, PT or partial thromboplastin time (PTT) should be within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (within days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Prothrombin time (PT) and activated partial thromboplastin time (aPTT) =< . X IULN, AND international normalized ratio (INR) =< . X IULN (unless subject is receiving anticoagulant therapy, as long as PT or PTT is within therapeutic range of intended use of anticoagulants) International normalized ratio (INR) or prothrombin time (PT) =< . x IULN unless patient is receiving anticoagulant therapy as long as INR or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x IULN unless patient is receiving anticoagulant therapy as long as INR or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy; as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy; as long as PT or PTT is within therapeutic range of intended use of anticoagulants, or subject is shown to have an antiphospholipid antibody on workup International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT)/activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants Performed within days prior to study registration up to the first dose of study drug: International normalized ratio (INR) =< . X ULN unless subject is receiving anticoagulant therapy as long as prothrombin time (PT) or partial prothrombin time (PTT) is within therapeutic range of intended use of anticoagulants Performed within days prior to study registration up to the first dose of study drug: Prothrombin time =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) of prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants; activated partial thromboplastin time (aPTT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants Performed within days of treatment initiation; international normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated partial thromboplastin time (aPTT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, should be performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Activated partial thromboplastin time (aPTT) and either international normalized ratio (INR) or PT =< . x IULN unless participant is receiving anticoagulant therapy as long as prothrombin time (PT) or aPTT is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or prothrombin time (PT) ?. ULN (unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants) International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants For high risk and very high risk CLL-IPI (Arms A and B) only; obtained ? days prior to randomization: prothrombin time (PT), international normalized ratio (INR), and partial thromboplastin time (PTT) ? . X ULN OR if patient is receiving anticoagulant therapy and PT or PTT is within therapeutic range of intended use of coagulants International normalized ratio (INR) or prothrombin time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or INR is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) ? . x ULN unless patient is receiving anticoagulant therapy as long as PT of partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anti-coagulant therapy as long as partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Prothrombin time (PT)/international normalized ratio (INR) and partial thromboplastin time (PTT) =< . x institutional ULN, unless the subject is on anticoagulant therapy; (if the subject is receiving anticoagulant therapy, PT, and activated PTT (aPTT) must be within therapeutic range of intended use of anticoagulants) International normalized ratio (INR) or prothrombin time (PT): =< . X ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) and activated partial thromboplastin time (aPTT) =< . x ULN unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, obtained =< days prior to registration International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy not requiring laboratory monitoring as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; therapeutic Coumadin is not acceptable International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) OR prothrombin time (PT) =< . x ULN unless participant is receiving anticoagulant therapy as long as PT or activated partial thromboplastin time (aPTT) is within therapeutic range of intended use of anticoagulants, specimens must be collected within days prior to the start of study treatment Within days prior to treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X institutional ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated partial thromboplastin time (aPTT) =< . X institutional ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants INR or PT: ?.xULN unless subject is receiving anticoagulant therapy, as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR)/prothrombin time (PT) =< . X ULN (unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time [PTT] is within therapeutic range of intended use of anticoagulants) International normalization ratio (INR) or prothrombin time (PT) . x upper limit of normal (ULN), unless the subject is receiving anticoagulant therapy, in which case PT and partial thromboplastin time (PTT)/ activated PTT (aPTT) must be within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (performed within days of treatment initiation) International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless participant is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (within days of treatment initiation) Within h of initiating study treatment: International normalized ratio (INR) or prothrombin time (PT) and activated partial thromboplastin time (aPTT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT and PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or activated partial thromboplastin time (aPTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) OR prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) ? . x ULN unless participant is receiving anticoagulant therapy as long as prothrombin time (PT) or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated partial thromboplastin time (aPTT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants, performed within days prior to registration Within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . X institutional ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (only if submitting to a biopsy), performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated PTT (aPTT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) and activated partial thromboplastin time (aPTT) less than or equal to . x ULN, unless patient is receiving anticoagulant therapy as long as PT or INR is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x upper limit of normal (ULN) unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants within days of treatment initiation International normalized ratio or prothrombin time (PT) ? . x ULN unless subject is receiving anticoagulant therapy and the PT or partial thromboplastin time (PTT) must be within the therapeutic range of the intended use of anticoagulants. Performed within days of treatment initiation: International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy in which case the INR or PT must be within the therapeutic range of intended use for the anticoagulant International normalized ratio (INR) or prothrombin time (PT) ? . ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x IULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) activated partial thromboplastin time (aPTT) =< . X ULN unless subject is receiving anticoagulant therapy, then as long as PT or PTT is within therapeutic range of intended use of anticoagulants =< . x ULN unless subject is receiving anticoagulant therapy, then as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR)/prothrombin time (PT) =< . times ULN unless participant is receiving anticoagulant therapy, as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants Patients must have prothrombin time (PT) / international normalized ratio (INR) and partial thromboplastin time (PTT) =< . x institutional upper limit of normal (IULN) unless the patient is on anticoagulant therapy within days prior to registration (if the patient is receiving anticoagulant therapy, PT, and a PTT must be within therapeutic range of intended use of anticoagulants) International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants (performed within days of treatment initiation) International normalized ratio (INR)/prothrombin time (PT) =< . x ULN (unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time [PTT] is within therapeutic range of intended use of anticoagulants) International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN, unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, obtained within days prior to C-AMT PET scan International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, obtained =< days prior to registration International normalized ratio (INR) OR prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of treatment initiation International normalized ratio (INR) or prothrombin time (PT) =< . x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International Normalized Ratio (INR) or Prothrombin Time (PT) ? . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants, performed within days of protocol enrollment International normalized ratio (INR) or prothrombin time (PT) =< . X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants