Patient must not have received any prior marrow-ablative chemotherapy and autologous hematopoietic cell transplant
Recipients of prior autologous hematopoietic stem cell transplantation are ineligible if disease recurrence occurred less than  months from their autologous stem cell transplant.
Intention to proceed to high dose chemotherapy (HDT) and autologous hematopoietic stem cell transplant (HSCT)
relapse within  year from frontline chemo-immunotherapy and ineligible for autologous hematopoietic stem cell transplant (auto-HSCT)
relapse within  year from frontline chemo-immunotherapy and ineligible for autologous hematopoietic stem cell transplant (auto-HSCT)
Has received prior autologous hematopoietic stem cell transplant within the last  days
Non-Hodgkin's lymphoma (NHL) in second or third complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant); relapsed double hit lymphomas; patients with options for treatment that are known to be curative are not eligible
Hodgkin's disease (HD): Induction failures, after first complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant), or those with active disease
Mantle cell lymphoma patients who are beyond first remission and previously treated with chemoimmunotherapy; patients who have relapsed following autologous hematopoietic cell transplant (HCT) are eligible
High dose therapy with autologous hematopoietic cell infusion (At least  days from last infusion prior to first dose of tazemetostat)
Prior autologous or allogeneic hematopoietic stem cell
Patients must not have a prior autologous, syngeneic or allogeneic hematopoietic stem cell transplant
History of relapsed or refractory CD+ malignancies (e.g. non Hodgkin lymphoma) who have failed prior treatment and require autologous hematopoietic stem cell transplant; evidence of disease not required (cohort )
Multiple myeloma (MM) stage II or III patients who have progressed after an initial response to chemotherapy or autologous hematopoietic stem cell transplantation (HSCT) or MM patients with refractory disease who may benefit from tandem autologous-nonmyeloablative allogeneic transplant
Stem cells from an identical donor could be used for autologous hematopoietic cell transplant (HCT)
Hodgkin's disease (HD): induction failures, second or third complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant)
Evidence of multiple myeloma disease progression (as defined by IMWG) any time prior to autologous (auto)-hematopoietic stem cell transplant (HSCT)
Prior allogeneic or autologous hematopoietic stem cell transplant in the last  months
Unless approved by the medical monitor, may not have received autologous hematopoietic stem cell transplant within  months before treatment
Autologous hematopoietic cell infusion after high dose therapy At least  days
Considered eligible for hematopoietic stem cell transplant (allogeneic or autologous) at the time of signing the ICF.
Received autologous hematopoietic stem cell transplant within the last  months
Prior autologous hematopoietic stem cell transplant ?  months.
Research participant did not have evidence of disease progression after salvage therapy and therefore underwent an autologous myeloablative transplantation with hematopoietic progenitor cell autologous (HPC[A]) rescue procedure
Non-Hodgkin's lymphoma - induction failures, second or third complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant)
Hodgkin's disease - induction failure, second or later complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant)
Hodgkin's disease (HD): induction failures, second or third complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant); or
Prior autologous hematopoietic stem cell transplant
Prior autologous or allogeneic hematopoietic stem cell transplant (HSCT)
Prior autologous hematopoietic stem cell transplant within  days of study entry
Autologous hematopoietic stem cell transplant or fludarabine chemotherapy within  months of study enrollment
Prior autologous hematopoietic stem cell infusion < weeks prior to first study dose
Prior autologous or allogeneic hematopoietic stem cell transplant
Receiving a G-CSF for one of the following indications:\r\n* Prevention/treatment of neutropenia along with treatment for leukemia or lymphoma\r\n* Mobilization of hematopoietic progenitor cells\r\n* Neutropenia prevention following autologous hematopoietic cell transplant
Scheduled to undergo either autologous or allogeneic hematopoietic stem cell transplant
Prior autologous or allogeneic hematopoietic stem cell transplant
Non-allogeneic (e.g. autologous) or syngeneic hematopoietic stem cell transplant (SCT) recipients
Non-allogeneic (e.g. autologous) or syngeneic hematopoietic stem cell transplant (SCT) recipients
Prior allogeneic or autologous hematopoietic stem cell transplant in past  months
Have documented or anticipated neutropenia expected to last for at least  days, following treatment in at least one of the following clinical situations: acute leukemia, myelodysplasia, severe aplastic anemia, recipients of Autologous hematopoietic stem cell transplant (HSCT), high risk neuroblastoma, advanced stage non-Hodgkin's lymphoma, hemophagocytic lymphohistiocytosis
Autologous hematopoietic stem cell transplant <  months prior to enrollment.