Participant must be aware of the nature of her malignancy, understand the study requirements and risks and be able and willing to sign a written informed consent document Subject must be able to understand and be willing to sign a written informed consent document Participant is able to understand and comply with study requirements and is willing to sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Subject must sign a written informed consent document Able to understand, and willing to sign, a written informed consent document. All subjects must be able to comprehend and sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Patients must be able to understand and the willingness to sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document Ability to understand and willing to sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Patients must be willing and able to understand the informed consent document Patient must be able to comprehend the approved consent document and have the willingness to sign it; the patient prior to enrollment and the administration of any protocol-specific therapy must sign the consent document All subjects must be able to comprehend and sign a written informed consent document Able to understand, and willing to sign a written informed consent document Patient must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and sign a written informed consent document and complete study-related procedures and questionnaires Able to understand and sign a written informed consent document. Patients must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Subjects must be able to understand and be willing to sign a written informed consent document Be able to understand and be willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Participants must be able to understand and willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document Patients must be able to understand and the willingness to sign a written informed consent document Informed consent: all subjects must be able to comprehend and sign a written informed consent document Able to understand and willingness to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document Patient needs to be able to understand and demonstrate willingness to sign a written informed consent document Patient needs to be able to understand and demonstrate willingness to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document. Ability to understand and willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Participants must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document. Patient must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Able to understand and to sign a written consent document Patients must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document RECURRENT/ PROGRESSIVE DIPG (STRATUM ): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines NON-PROGRESSED DIPG (STRATUM ): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines All subjects must be able to comprehend and sign a written informed consent document Patient must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Ability to understand and willing to sign a written informed consent document Ability to understand and willing to sign a written informed consent document Be able to understand a written informed consent document and the willingness to sign it All subjects must be able to comprehend and sign a written informed consent document Able to understand and willing to sign a written informed consent document Be able to understand and have willingness to sign a written informed consent document Patients must be able to understand and the willingness to sign a written informed consent document The ability to understand and be willing to sign an informed consent document Able to understand and willing to sign a written informed consent document All subjects must be able to comprehend and sign a written informed consent document Participants must be able to understand and willing to sign a written informed consent document Participants must be able to understand and be willing to sign a written informed consent document Patients must have the ability to understand English, sign a written informed consent document, and be willing to follow protocol requirements The patient understands the study requirements and is willing and able to sign an informed consent document Sign a written informed consent document Participants must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Ability of subject to understand and willing to sign a written informed consent document AIMS AND : Participants must be able to understand and willing to sign a written informed consent document AIM : Participants must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Must be able to understand and sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document to participate Patients who are able to understand the investigational nature of this study and agree to sign a written informed consent document