History of hemoptysis within the last month History of gross hemoptysis. Evidence of hemoptysis within the last days. History of hemoptysis within the last month prior to randomization Has history bleeding disorders (e.g., pulmonary hemorrhage, significant hemoptysis, menometrorrhagia not responding to hormonal treatment) ? months before CD History of hemoptysis or any significant bleeding within the last month prior to enrollment Pulmonary hemorrhage or hemoptysis > . mL blood within weeks (or within weeks if source definitively treated [eg, radiation therapy or bronchoscopic procedure]) History of known hemoptysis, gastrointestinal or intracerebral hemorrhage Patients with active hemoptysis ARM B COHORT : Patients must not have active clinically significant hemoptysis PHASE I STUDY ELIGIBILITY CRITERIA:\r\nSignificant hemorrhage (> mL bleeding/episode within months before study enrollment) or hemoptysis (> mL fresh blood within days before study enrollment) Pulmonary hemorrhage or hemoptysis > . ml blood within weeks unless cause has been addressed and is medically resolved. Patient must not have had clinically significant hemoptysis, defined as greater than tablespoon of bright red blood, within one year prior to registration; although hemoptysis has not been associated with cediranib, it may be a class effect for anti-angiogenic agents and therefore a risk factor for this experimental agent Has hemoptysis within weeks prior to randomization. Recent hemoptysis History of gross hemoptysis within months of study entry. History of pulmonary hemorrhage or hemoptysis within months of starting study treatment Patients with hemoptysis within days prior to entering the study Grade or hemoptysis or hemorrhage within weeks prior to study entry History of hemoptysis Patients with hemoptysis within days prior to entering the study Patients with active bleeding, including hemoptysis within weeks of enrollment should be excluded, as there is no safety data with vorinostat in this setting Hemoptysis within weeks Participants with a history of gross hemoptysis within months prior to study treatment Baseline hemoptysis, per clinician/investigator evaluation Pulmonary hemorrhage or gross hemoptysis within months History of hemoptysis greater than or equal to (>/=) grade within months of randomization Active hemoptysis Pulmonary hemorrhage or gross hemoptysis within months prior to enrollment Active hemoptysis or history of clinically relevant hemoptysis as determined by the treating physician; patients who had history of transient minor hemoptysis after bronchoscopic biopsy are eligible unless deemed otherwise by the treating physician Pulmonary hemorrhage or hemoptysis > . mL blood within six weeks unless cause has been addressed and is medically resolved Coughed up blood from lungs (also called hemoptysis) within the past year prior to enrollment