Patients with mental deficits or psychiatric conditions that preclude them from giving informed consent or following protocol Patients have voluntarily agreed to participate by giving written informed consent. Subjects must be willing to sign and provide informed consent and be capable of giving informed consent in accordance with the Institutional Review Board/Ethics Committee policy A patient must be capable of giving informed consent or have an acceptable surrogate capable of giving consent on the subjects behalf Any mental or medical condition that prevents the subject from giving informed consent or participating in the trial. Patients with mental deficits and/or psychiatric history that preclude them from giving informed consent or from following protocol Must be capable of giving consent to participate in the study Has any mental or medical condition that prevents the patient from giving informed consent or participating in the trial Patients must be capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form. Patients must be capable of giving informed consent and be willing and able to comply with schedule Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form Patient, or patient's authorized representative, must be willing and capable of giving written Informed Consent and must be able to adhere to dosing and visit schedules as well as meet all study requirements Capable of giving written informed consent prior to any study-specific procedures Capable of giving signed informed consent Psychiatric illness, which would prevent the patient from giving informed consent Has any mental or medical condition that prevents the patient from giving informed consent Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form Patient has voluntarily agreed to participate by giving written informed consent/assent for the trial Patient capable of giving informed consent Patient capable of giving informed consent Capable of informed consent Patient has voluntarily agreed to participate by giving written informed consent Patients must be capable of informed consent Capable of giving signed informed consent which includes compliance with the requirements and restrictions specified. Additional Inclusion criteria for Subjects in Part : Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form Subjects who have voluntarily agreed to participate by giving written informed consent. Adults capable of giving informed consent. Capable of giving signed informed consent. Patient is capable of giving informed consent Capable of giving written informed consent Able to give informed consent (if > years), or with a legal guardian capable of giving informed consent (if < years) DONOR: Donors able to give informed consent (if > years), or with a legal guardian capable of giving informed consent (if < years) Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form. If the subject is less than years old, an Assent form and parental/guardian Consent form (replacing \you will\ with \your child will\ will be required). Matched Related Donor: Capable of giving written, informed consent Subject has voluntarily agreed to participate by giving written informed consent Capable of giving informed consent Capable of giving written informed consent, which includes compliance with the requirements and restrictions Has any mental or medical condition that prevents the subject from giving informed consent or participating in the trial Any mental or medical condition that prevents the subject from giving informed consent or participating in the trial. Patient must be capable of, and must voluntarily agree to participate by giving written informed consent Patient is capable of giving informed consent. Capable of compliance with the requirements and restrictions listed in the consent form; Patients must be capable of signing an informed consent Adult patients who are capable of giving consent Capable of giving signed, written informed consent Capable of giving informed consent Subjects must be capable of giving informed consent Capable of giving informed consent Subjects are capable of giving informed consent or have an acceptable surrogate capable of giving consent on the subjects behalf Not giving consent for study participation Subjects are capable of giving informed consent Women with psychological, psychiatric, or other conditions which prevent giving fully informed consent Subjects are capable of giving informed consent. Incapable of giving informed consent Psychiatric illness that would prevent the patient from giving informed consent Capable of giving informed consent Subjects capable of giving informed consent Capable of informed consent Subject capable of giving informed consent and participating in the process of consent Subject capable of giving informed consent and participating in the process of consent Individuals who are not willing or capable of giving informed consent or assent (with legal guardian consent) Subjects incapable of giving informed written consent Patients are capable of giving informed consent Patients are capable of giving informed consent