History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease Patients with history of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae are NOT eligible for the study History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease (i.e. stroke or transient ischemic attack [TIA]) in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease or event with significant symptoms History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease in the past months or ongoing event with active symptoms or sequelae History of significant cerebrovascular disease or event with significant symptoms or sequelae.*