Creatinine =< . x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= mL/min Creatinine =< . x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > mL/min using the lean body mass formula only Serum creatinine =< . x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= ml/min, obtained within weeks prior to randomization Creatinine =< upper limit of normal (ULN) or calculated creatinine clearance >= mL/min Creatinine =< institutional upper limit normal (ULN), CTCAE v . grade ; NOTE: if creatinine > ULN, creatinine clearance must be > mL/min Creatinine =< . x upper limit of normal (ULN) mg/dL OR calculated (calc.) creatinine clearance >= mL/min Serum creatinine =< . x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= mL/min, within weeks of randomization Creatinine =< . times institutional upper limit of normal (ULN) OR calculated creatinine clearance >= mL/min Serum creatinine =< . x the upper limit of normal or calculated creatinine clearance >= mL/min Serum creatinine ? . x upper limit of normal (ULN) or calculated creatinine clearance ? mL/minute Serum creatinine ? . upper limit of normal (ULN) or creatinine clearance (CrCl) ? mL/min/. m Measured within days prior to registration: serum or plasma creatinine =< . x institutional upper limit of normal (ULN) OR creatinine clearance >= mL/min/. m^ for participants Creatinine =< . x the institutional upper limit of normal (ULN), or -hr clearance >= mL/min, within days of registration Creatinine =< . x upper limit of normal OR creatinine clearance >= mL/min Serum creatinine >= . times the upper normal limit or calculated/measured creatinine clearance =< mL/min Serum creatinine or creatinine clearance =< institutional upper limit or >= mL/min creatinine clearance for patients with serum creatinine > institutional upper limit Serum creatinine =< . x institutional upper limit of normal (ULN) OR calculated creatinine clearance >= mL/min for subjects with creatinine levels > . x institutional ULN within days of treatment initiation and must be independent of hematopoietic growth factor support Creatinine within the institution's laboratory upper limit of normal (ULN) or calculated creatinine clearance > ml/min Serum creatinine ?. institutional upper limit of normal (ULN) or calculated creatinine clearance > mL/min. Serum creatinine =< . x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= mL/min for subject with creatinine levels > . x institutional ULN Either creatinine < . x institutional upper limit of normal (ULN) or creatinine clearance > mL/min as calculated by institutions standard formula Serum creatinine =< x upper limit of reference range or creatinine clearance >= ml/min COHORT : HORMONE RECEPTOR POSITIVE BREAST CANCER: Serum creatinine =< . X upper limit of normal (ULN), or measured creatinine clearance >= mL/min/ COHORT : TRIPLE NEGATIVE BREAST CANCER: Serum creatinine =< . X upper limit of normal (ULN), or measured creatinine clearance >= mL/min/ COHORT : ENDOMETRIAL CANCER: Serum creatinine =< . X upper limit of normal (ULN), or measured creatinine clearance >= mL/min/ Serum creatinine =< . x institutional upper limit of normal (IULN) and creatinine clearance >= mL/min Creatinine OR calculated creatinine clearance =< . x upper limit of normal (ULN) OR >= mL/min for subject with creatinine levels > . x institutional ULN. Creatinine clearance should be calculated per institutional standard. Serum creatinine < x upper limit of normal (ULN) or estimated creatinine clearance > ml/min as calculated using the method standard for the institution Within days of the first dose of study drug: Serum creatinine =< . times the upper limit of normal or estimated creatinine clearance (CrCL) > mL/min Creatinine within institutional normal limits or, clearance > mL/ minute if serum creatinine is elevated above institution upper limit (UL) Creatinine =< . x the institutional upper limit of normal (ULN) OR creatinine clearance > ml/min within days of cycle day Cockcroft calculated creatinine clearance of >= ml/min or . x the upper limit of normal (ULN) Serum creatinine =< x upper limit of normal (ULN) or estimated creatinine clearance >= mL/min as calculated using the method standard for the institution Serum creatinine >= . x upper limit of normal (ULN) OR calculated creatinine clearance =< mL/min for patients with creatinine levels > . x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard Serum creatinine =< . x institutions upper limit of normal (ULN), or creatinine clearance >= ml/min Creatinine level =< upper limit of normal (ULN): if creatinine > ULN, creatinine clearance must be > ml/min Serum creatinine =< . x laboratory upper limit of normal or calculated creatinine clearance of >= ml/min/. m^) Adequate renal function defined as: Serum creatinine ? . x ULN (upper normal limit) or calculated creatinine clearance (determined by MDRD) > mL/min/.m. Serum creatinine =< upper limit of normal (ULN) for the lab or a calculated creatinine clearance >= mL/min Serum creatinine =< . x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= mL/min for patient with creatinine levels > . x institutional ULN Serum creatinine =< . X upper limit of normal (ULN), or measured creatinine clearance >= mL/min/. m^ Creatinine less than or equal to . x upper limit of normal (ULN) with calculated creatinine clearance greater than ml/min Serum creatinine =< . x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= mL/min for subjects with creatinine levels > . x ULN within days of treatment initiation Serum creatinine < . times the upper limit of normal (ULN) (or a calculated creatinine clearance >= mL/min) Creatinine clearance >= ml/min or serum creatinine =< . x upper limit of normal (ULN) Serum creatinine >= ULN and/or calculated or measured creatinine clearance < % lower limit of normal (LLN) Creatinine =< . x upper limit normal (ULN) or measured creatinine clearance (CrCl) of >= ml/m^/. m^ Creatinine =< . x the upper limit of normal (ULN) OR \r\n* Estimated creatinine clearance of > ml/min\r\n* Patients with renal dysfunction deemed to be the result of disease will be considered eligible Creatinine clearance >= mL/min/.m^ for patients with creatinine >= . x upper limit of normal Serum creatinine =< . x the upper limit of normal or calculated creatinine clearance >= mL/min Serum creatinine =< . times upper limit of normal or calculated creatinine clearance >= ml/min Creatinine =< . x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= mL/min Renal: Serum/plasma creatinine (sCr) ?. x upper limit of normal, or creatinine clearance (Ccr) ? mL/min. Biochemistry: Total bilirubin* ? institutional upper limit of normal Alkaline phosphatase ? . x institutional upper limit of normal AST(SGOT) and ALT(SGPT) ? . x institutional upper limit of normal Creatinine Clearance ? ml/min * excluding Gilbert's syndrome Creatinine clearance to be measured directly by hour urine sampling or as calculated by Cockcroft Formula: Females: GFR = . x (-age) x weight in kg serum creatinine in ?mol/L Males: GFR = . x (-age) x weight in kg serum creatinine in ?mol/L Serum creatinine =< . times the upper limit of normal or estimated creatinine clearance (CrCl) > mL/min within days of the first dose of study drug Calculated creatinine clearance (absolute value) of >= mL/minute or creatinine < . mg/dl or < times upper limit of normal for the research participant's age group Serum creatinine < . times upper limit of normal range (ULN) or creatinine clearance >= ml/min Creatinine < . x the upper limit of normal (ULN) or calculated creatinine clearance of >= ml/min Serum creatinine =< . x upper limit of normal OR creatinine clearance on a -h urine collection of >= mL/min Serum creatinine =< . x the upper limit of normal or calculated creatinine clearance >= ml/min Serum creatinine =< . x upper limit of normal (ULN) OR calculated creatinine clearance >= mL/min for patients with creatinine levels > . x institutional ULN Serum creatinine =< . x upper limit of normal (ULN) OR calculated creatinine clearance >= mL/min for patients with creatinine levels > . x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard Serum creatinine =< . X upper limit of normal (ULN) or creatinine clearance > mL/min Creatinine clearance >= mg/dl OR serum creatinine =< . x upper limit of normal (ULN) Adequate renal function (creatinine =< . upper limit of institutional normal [ULIN] or calculated creatinine clearance > ml/min) Serum creatinine =< . x institutional upper limit normal (ULN) and calculated creatinine clearance of >= mL/min Renal: serum creatinine within normal limits (WNL), defined as within % of the institution's stated reference range, or a calculated creatinine clearance > mL/min/. m for patients with abnormal, increased, creatinine levels. Patients with Multiple Myeloma (only): serum creatinine ? . the institutional upper limit of the normal range and a calculated creatinine clearance > mL/min/. m. Renal insufficiency (creatinine clearance < ml/min) or liver insufficiency (serum bilirubin > times the upper normal range and/or serum transaminases (AST/SGOT, ALT/SGPT, but not gamma Glutamyl Transpeptidase) > times the upper normal range). Creatinine clearance may be calculated according to validated formulas (Crockoft's or MDRD) Creatinine ?. times the upper limit of normal (ULN) and/or creatinine clearance ? mL/min Serum creatinine > . x upper limit of normal or estimated creatinine clearance (CrCl) < ml/min REGISTRATION TO TREATMENT (STEP ): Serum creatinine =< . X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= mL/min for patient with creatinine levels > . X ULN, within days prior to first dose of pembrolizumab REGISTRATION TO TREATMENT (STEP ): Serum creatinine =< . X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= mL/min for patient with creatinine levels > . X ULN, within days prior to first dose of pembrolizumab Creatinine =< . x upper limit of normal (ULN) OR >= mL/min Within days of treatment initiation: If serum creatinine concentration >= . x upper limit of normal (ULN), then estimated creatinine clearance must be >= mL/min for subject with creatinine levels > . x institutional ULN Creatinine =< . x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= mL/min Creatinine OR =< . mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > mL/min Serum creatinine =< . x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= ml/min Creatinine =< . x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= mL/min Creatinine < . x ULN OR creatinine clearance measured >= mL/minute for patients with creatinine levels >= . x upper limit of normal Creatinine =< . x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance > mL/min Serum creatinine =< . x ULN or calculated or directly measured creatinine clearance (CrCl) >= % LLN (lower limit of normal) Creatinine =< . times the upper limit of normal (ULN) OR creatinine clearance >= mL/min/. m^ Serum creatinine >= . times the upper normal limit or calculated/measured creatinine clearance =< mL/min Serum creatinine =< . x upper limit of normal OR creatinine clearance on a -h urine collection of >= mL/min Serum creatinine =< . x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= ml/min Creatinine =< institutional upper limit normal (ULN); note: if creatinine > ULN, creatinine clearance must be > mL/min Creatinine < . x the upper limit of normal (ULN) or calculated creatinine clearance of >= ml/min Serum creatinine =< . x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= mL/min obtained within days prior to registration Serum creatinine =< . X upper limit of normal (ULN) OR measured or calculated creatinine clearance >= mL/min for subject with creatinine levels > . X institutional ULN Creatinine =< . mg/dL x upper limits of normal (ULN) OR calculated (calc.) creatinine clearance >= mL/min Creatinine > . x the upper limit of normal; patients with creatinine > . x the upper limit of normal who have creatinine clearance >= cc/min (calculated using the Cockcroft and Gault equation) are eligible Serum creatinine =< . x upper limit of normal (ULN) for the lab, calculated creatinine clearance >= mL/min or -hour creatinine clearance >= mL/min Have calculated creatinine clearance (CrCL) ? mL/minute or serum creatinine ?. times below the upper limit of normal. Serum creatinine ? . upper limit of normal (ULN) or creatinine clearance (CrCl) ? mL/min/. m Serum creatinine ? . x upper limit of normal (ULN) or calculated creatinine clearance ? mL/minute Serum creatinine =< . x institutional upper limit of normal concurrent with creatinine clearance >= mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > . x upper limit of normal (ULN), within days of study registration Creatinine <. X upper limit of normal or estimated plasma creatinine clearance of ? mL/min At least weeks ( days) prior to registration: Serum creatinine =< . x ULN or calculated or directly measured creatinine clearance (CrCl) >= % LLN (lower limit of normal) Serum creatinine ? . age-adjusted upper limit of normal (ULN) OR calculated creatinine clearance > mL/min Serum creatinine =< . x the upper limit of normal range, or, if serum creatinine > . x the upper limit or normal range, then the creatinine clearance must be >= mL/min Renal: Serum creatinine (sCr) ?. x upper limit of normal, or creatinine clearance (Ccr) ? mL/min. Creatinine =< . x upper limit of normal OR creatinine clearance >= mL/min/.m^ for patients with creatinine >= . x upper limit of normal Serum creatinine =< . x upper limit of normal OR calculated creatinine clearance >= ml/min Serum creatinine =< . x the upper limit of normal (ULN) or calculated creatinine clearance >= mL/min Serum creatinine of ?. the upper limit of normal (ULN)OR estimated creatinine clearance (CrCl) ? ml/min/. m Serum creatinine =< . x upper limit of normal (ULN) or calculated creatinine clearance >= mL/min Serum creatinine =< . x the upper limit of normal or creatinine clearance >= mL/min (measured or calculated) Serum creatinine =< . x the upper limit of normal or calculated creatinine clearance >= mL/min Serum creatinine ?. x upper limit of normal (ULN) or a calculated creatinine clearance > mL/min, Creatinine =< . x laboratory upper limit of normal or calculated creatinine clearance of >= ml/min Serum creatinine =< . x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= ml/min (drug is not cleared by the kidney) Serum creatinine <. x upper limit of normal (ULN) or estimated creatinine clearance mL/min (as calculated using the standard method of the institution); Patient's serum creatinine must be ? . x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than . times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? mL/min/.m. Adequate renal function defined as serum creatinine ? .x upper limit of normal (ULN) for age. If the serum creatinine is above these values, the calculated creatinine clearance or radioisotope GFR must be ? mL/min/.m. Creatinine =< . x upper limit of normal (ULN); either lab result or calculated clearance Serum creatinine > . x ULN and/or measured or calculated creatinine clearance < % LLN (lower limit of normal) Bone marrow function: Creatinine =< . x laboratory upper limit of normal or calculated creatinine clearance of >= mL/min (please use institutional formula) Calculated creatinine clearance (CrCl) of greater than or equal to or serum creatinine less than x ULN; even if organ function abnormalities are considered due to tumor, the upper limit for creatinine is less than or equal to mg/dL Creatinine > . times upper normal limit and creatinine clearance < ml/min/m^; patients with creatinine > times upper limit of normal will have creatinine clearance estimated; at the discretion of treating physician, creatinine clearance can be measured and that value can be used instead of calculated creatinine clearance Creatinine =< . x laboratory upper limit of normal or calculated creatinine clearance of >= ml/min Serum creatinine =< . x upper limit of normal (ULN), or, calculated creatinine clearance (CrCl) >= mL/min Serum Creatinine < . x ULN (upper limit of normal) or estimated creatinine clearance ? mL/min, as calculated using method standard for the institution (Appendix ). Patient's serum creatinine must be ? . x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than . times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? mL/min/.m. Creatinine =< . x upper limit of normal (ULN) or creatinine clearance >= ml for patients with creatinine levels . times above institutional ULN (calculated based on age, weight and sex) Serum creatinine ? . x upper limit of normal (ULN) or calculated creatinine clearance > mL/min if the serum creatinine is > . x ULN Serum creatinine >= . times the upper normal limit or calculated/measured creatinine clearance =< mL/min Serum creatinine =< . x upper limit of normal OR creatinine clearance on a -h urine collection of >= mL/min Creatinine < . x upper limit of normal and/or a creatinine clearance >= ml/min Serum creatinine less than . x upper limit of normal (ULN), OR -hour creatinine clearance = or mL/min for subject with creatinine levels more than . x ULN; (Note: creatinine clearance need not be determined if the\r\nbaseline serum creatinine is within normal limits; creatinine clearance should be determined per institutional standard) Serum creatinine > . x upper limit of normal (ULN) or creatinine clearance < mL/minute Creatinine value of =< . x upper limit of normal (ULN) or creatinine clearance value of >= mL/min Serum creatinine < . x upper limit of normal (ULN) or a calculated creatinine clearance >= mL/min Serum creatinine =< . x institutional upper limit of normal concurrent with creatinine clearance >= mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > . x upper limit of normal (ULN) (within days of study registration) Serum creatinine =< . x ULN or calculated or directly measured creatinine clearance (CrCl) >= % of LLN (lower limit of normal)