Female patients must either be of non-reproductive potential (i.e., post-menopausal by history: greater than or equal to  years old and no menses for greater than or equal to  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must be either of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
COHORT : HORMONE RECEPTOR POSITIVE BREAST CANCER: Female patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence during the study and for and for at least  weeks after the final dose of any study-related medications; male patients must use at least two forms of contraception during the study and for at least  weeks after the final dose of any study-related medications or have a partner who is not of reproductive potential
COHORT : TRIPLE NEGATIVE BREAST CANCER: Female patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence during the study and for and for at least  weeks after the final dose of any study-related medications; male patients must use at least two forms of contraception during the study and for and for at least  weeks after the final dose of any study-related medications or have a partner who is not of reproductive potential
COHORT : ENDOMETRIAL CANCER: Female patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence during the study and for and for at least  weeks after the final dose of any study-related medications; male patients must use at least two forms of contraception during the study and for and for at least  weeks after the final dose of any study-related medications or have a partner who is not of reproductive potential
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative urine/serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative urine pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test within  weeks prior to starting treatment
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry. If unsure postmenopausal status, hormone levels will be employed to verify
Female subjects who are of non-reproductive potential (ie, post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); OR female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; AND/OR history of hysterectomy, AND/OR history of bilateral tubal ligation, AND/OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum or urine pregnancy test within  hours prior to the first study drug administration
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test within  days of study treatment, confirmed prior to treatment on day 
Female subjects who are of non-reproductive potential (ie, post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) OR must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (ie, post menopausal by history - no menses for ?  year and follicle-stimulating hormone (FSH) level consistent with post-menopausal status; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy).
Subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: ?  years old and no menses for ?  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
PHASE I STUDY ELIGIBILITY CRITERIA:\r\nFemale patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence for female patients with reproductive potential
PHASE II STUDY COHORT  OVARIAN CANCER ELIGIBILITY CRITERIA (MEDI+O, MEDI+C AND MEDI+O+C):\r\nFemale patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence for female patients with reproductive potential
PHASE II STUDY COHORT  TRIPLE NEGATIVE BREAST CANCER ELIGIBILITY CRITERIA (MEDI+O ONLY):\r\nFemale patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence for female patients with reproductive potential
PHASE II STUDY NON-SMALL CELL LUNG CANCER (COHORT ; MEDI+O AND MEDI+C) AND SMALL CELL LUNG CANCER (COHORT ; MEDI+O ONLY) ELIGIBILITY CRITERIA:\r\nFemale patients must either be of non-reproductive potential (i.e., post-menopausal by history: >= years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence for female patients with reproductive potential
PHASE II COLORECTAL CANCER COHORT  (MEDI+C ONLY):\r\nFemale patients must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry and agree to use contraception or abstinence for female patients with reproductive potential
Female patients must either be of non-reproductive potential (ie, post-menopausal by history: ? years old or no menses for  year without an alternative medical cause; OR history of complete hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
Female patients must either be of non-reproductive potential (i.e., post-menopausal by history: greater than or equal to  years old and no menses for greater than or equal to  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
Alternatively, female subjects must be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy)
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); or, female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >= year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry.
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >= years old and no menses for >  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative urine or serum pregnancy test upon study entry
Women must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry (minimum sensitivity  IU/L or equivalent units of human chorionic gonadotropin [HCG])
Female patients who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy) must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  year; OR history of hysterectomy; or history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Women must not be pregnant or breast-feeding; female patients of childbearing potential must have a negative serum pregnancy test within  weeks prior to registration to rule out pregnancy; female patients who are of non-reproductive potential are those who are post-menopausal by history (i.e. no menses for >=  year); OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy
Female subjects must either be of non-reproductive potential (i.e. post-menopausal by history: >=  years old and no menses for  > year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test within  weeks prior to starting treatment.
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e., post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (i.e., post-menopausal by history - no menses for >=  years; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female patients must either be of non-reproductive potential (i.e. post-menopausal by history of age >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test (beta-human chorionic gonadotropin [HCG]) at the screening visit; if screening visit pregnancy test was completed within  days of first treatment visit it does not need to be repeated; patients with a negative pregnancy test at screening beyond  days prior to treatment, but who otherwise meet all other criteria, may be registered to study but must have a repeat negative serum pregnancy test within  days of treatment and such testing may be done on day of first treatment prior to administration)
Female subjects must either be of non-reproductive potential (ie, post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects must either be of non-reproductive potential (i.e. post-menopausal by history: >=  years old and no menses for >=  year without an alternative medical cause; OR history of hysterectomy, OR history of bilateral tubal ligation, OR history of bilateral oophorectomy) or must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (ie, post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); or, female subjects of childbearing potential must have a negative serum pregnancy test upon study entry
Female subjects who are of non-reproductive potential (ie, post-menopausal by history - no menses for >=  year; OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy); female subjects of childbearing potential must have a negative serum pregnancy test upon screening