DONOR: Donors must meet all criteria for donation as per  Code of Federal Regulations (CFR) Subpart C
DONOR: Donors who do not meet  CFR  Subpart C requirements per the Food and Drug Administration (FDA) to donate
DONOR: Regarding donation eligibility, is identified as either:\r\n* Completed the process of donor eligibility determination as outlined in  Code of Federal Regulations (CFR)  and agency guidance; OR\r\n* Does not meet  CFR  eligibility requirements, but has a declaration of urgent medical need completed by the principal investigator or physician sub-investigator per  CFR 
DONOR: Identified as either:\r\n* Completed the process of donor eligibility determination as outlined in  Code of Federal Regulations (CFR)  and agency guidance; OR\r\n* Does not meet  CFR  eligibility requirements, but has a declaration of urgent medical need completed by the principal investigator or physician sub-investigator per  CFR 
DLI DONOR: The patients stem cell donor must be capable of providing informed consent; potential donors under the age of  must have a single patient exemption approved by the Institutional Review Board (IRB) and the donor and a guardian must provide assent; the donor selection process will be compliant with  Code of Federal Regulations (CFR) 
The donor-recipient Human Leukocyte Antigen (HLA) match criteria required for participation in this protocol are not research subjects in this study and they must meet criteria as National Marrow Donor Program (NMDP) donors. Procedures for selection of donors and stem cell dose will follow FDA Code of Federal Regulations requirements for Blood Products ( CFR ) and Human Cellular and Tissue Based Products ( CFR ). The standard institutional practices for stem cell transplants also will be followed. The donors are:
DONOR: Donor selection will be in compliance with  Code of Federal Regulations (CFR) 
DONOR: Donors who fail eligibility requirements for donation of cells or tissue per section  Code of Federal Regulations (CFR)  for donation of a HCT/product (P) will be excluded unless use of the cells complies with  CFR .(b)(iii) (urgent medical need) or with  CFR .(b)(i) (allogeneic use in a first-degree or second-degree relative)
MSC DONOR: donor must meet the selection and eligibility criteria as defined by the Foundation for the Accreditation of Hematopoietic Cell Therapy (FACT) and Food and Drug Administration (FDA)  Code of Federal Regulations (CFR) Part 
INCLUSION CRITERIA - HPC-A CELL DONOR: Meets donation eligibility requirements as outlined by  Code of Federal Regulations (CFR) 
DONOR: meets donation eligibility requirements as outlined by  Code of Federal Regulations (CFR)  and agency guidance
DONOR: Regarding donation eligibility, is identified as either:\r\n* Completed the process of donor eligibility determination as outlined in  case report form (CFR)  and agency guidance; OR\r\n* Does not meet  CFR  eligibility requirements, but has a declaration of urgent medical need completed by the principal investigator or physician sub-investigator per  CFR 
Has a partially HLA-matched single UCB unit (>=  of ) with adequate cell dose; UCB units must fulfill eligibility as outlined in  Code of Federal Regulations (CFR)  and agency guidance
Regarding eligibility, is identified as either:\r\n* Completed the process of donor eligibility determination as outlined in  CFR  and agency guidance; OR\r\n* Does not meet  CFR  eligibility requirements, but has a declaration of urgent medical need completed by the principal investigator or physician sub-investigator per  CFR 
DONOR: Has completed the process of donor eligibility determination as outlined in  Code of Federal Regulations (CFR)  and agency guidance; OR
DONOR: Does not meet  CFR  eligibility requirements, but has a declaration of urgent medical need completed by the principal investigator or physician sub-investigator per  CFR 
DONOR: Donor selection will be in compliance with  Code of Federal Regulations (CFR) 
Individuals with normal skin and Fitzpatrick skin type II, III or IV ( Code of Federal Regulations [CFR] .)
DONOR: Eligible donors will include siblings age >=  matched with the recipient at human leukocyte antigen (HLA)-A, B, C, and DRB\r\n* Donor selection and stem cell product transplantation will be in compliance with  Code of Federal Regulation (CFR) 
Participants/volunteers from the vulnerable population, as defined by  Code of Federal Regulations (CFR)