Resolution of all chemotherapy-related or radiation-related toxicities to grade severity or lower, except for stable sensory neuropathy (=< grade allowed) and alopecia (of any grade) Resolution of all chemotherapy-related or radiation-related toxicities to grade severity or lower, except for stable sensory neuropathy (=< grade ) and alopecia Received prior chemotherapy, an immune checkpoint inhibitor, or radiation therapy within weeks prior to study registration or who has not recovered (i.e., ? Grade or at baseline) from adverse events from previously administered agents. NOTE: Subjects with alopecia, grade ? sensory neuropathy or other grade ? AEs not constituting a safety risk based on investigator judgement are an exception to this criterion and can still be considered for the study. Patients must have recovered from adverse events due to prior treatment to ? grade , except for alopecia and sensory neuropathy ? grade Patients must have recovered from adverse events attributable to previous treatment to =< grade , except for alopecia and sensory neuropathy =< grade Have resolution of all previous treatment-related toxicities to Grade severity or lower, except for stable sensory neuropathy (less than or equal to Grade ) or alopecia. If subject received major surgery or radiation therapy of > Gy, must have recovered from the toxicity and/or complications from the intervention. Recovered from any previous therapy related toxicity to =< grade or baseline at study entry (except for stable sensory neuropathy =< grade and alopecia) Subjects who are receiving any concurrent investigational or conventional agent with known or suspected activity against multiple myeloma, or those whose adverse events due to agents administered more than weeks earlier have not recovered to a severity of grade or grade ; subjects with chronic grade toxicities may be eligible per discretion of the investigator and M. D. Anderson Cancer Center (MDACC) Investigational New Drug (IND) Office (eg, grade chemotherapy-induced neuropathy) Persistent grade > clinically significant toxicities related to prior antineoplastic therapies (except for alopecia); stable sensory neuropathy ? grade NCI-CTCAE v. . is allowed. Patients who have not recovered from adverse events due to prior anti-cancer therapy (i.e., have residual toxicities > grade excepting alopecia, peripheral sensory neuropathy, and stable endocrine insufficiencies such as thyroid and adrenal insufficiency) Patients must have recovered to =< grade adverse events or to =< grade alopecia and sensory neuropathy due to prior treatment The patient has not recovered from adverse events related to prior therapy to Grade ? (excluding Grade alopecia and neuropathy) Patients must have recovered from adverse events attributable to previous treatment to =< grade , except for alopecia and sensory neuropathy =< grade Adverse events except for sensory neuropathy from any previous treatments must be resolved or stabilized to Grade less than equal to ( Gy, must have recovered from the toxicity and/or complications from the intervention. Patients must have recovered from adverse events attributable to previous treatment to =< grade , except for alopecia and sensory neuropathy =< grade Resolution of all chemotherapy-related or radiation-related toxicities to Grade severity or lower, except for stable sensory neuropathy (<= Grade ) and alopecia. Recovered from any previous therapy related toxicity to <= Grade at study entry (except for stable sensory neuropathy <= Grade and alopecia) Chemotherapy-related or radiation-related toxicities that have not resolved to grade severity or lower, except for stable sensory neuropathy (=< grade ) and alopecia