Patients with a history of the following within =< months of study entry are not eligible:\r\n* Arterial thromboembolic events\r\n* Unstable angina\r\n* Myocardial Infarction No angina or myocardial infarction within days of registration; in view of potential cardiac risk with lenalidomide, patients with stable angina will be excluded History of myocardial infarction or unstable angina within months prior to day Unstable angina or myocardial infarction. Must not have a history of myocardial infarction, severe or unstable angina, peripheral vascular disease or familial QT prolongation Myocardial infarction of unstable angina within months prior to the planned start date of study drug. Any comorbidity or condition which, in the opinion of the investigator, may interfere with the assessments and procedures of this protocol e.g. unstable angina, myocardial infarction within months, severe infection, etc. Myocardial infarction or unstable angina within months of the first date of treatment on this study. History of cerebral vascular accident, unstable angina, myocardial infarction, or ventricular arrhythmia within the last months Having known myocardial infarction or unstable angina within months before first ZW dosing History of myocardial infarction or unstable angina within months of registration History of myocardial infarction or unstable angina within months prior to day Has a history of myocardial infarction or unstable angina within months before enrollment Patients with unstable angina and/or myocardial infarction within months prior to screening History of myocardial infarction or unstable angina within months prior to first study treatment Unstable angina or a history of myocardial ischemia within prior months History of myocardial infarction or unstable angina within months prior to cycle , day Myocardial infarction or unstable angina within months of enrollment Arterial ischemic event (e.g., unstable angina, myocardial infarction, stroke) within months of study entry Myocardial infarction within the past months, or stable or unstable angina History of myocardial infarction or severe unstable angina Patients with a history of myocardial infarction, unstable angina, or uncontrolled arrhythmia within months from enrollment. ST elevation myocardial infarction within days prior to enrollment; unstable angina or significant, untreated arrhythmias within days prior to enrollment History of myocardial infarction or unstable angina within months prior to study enrollment History of myocardial infarction or unstable angina within the past months History of myocardial infarction or unstable angina within months prior to day Patients with a myocardial infarction or unstable angina within months of study entry Unstable angina or a history of myocardial ischemia within prior months Myocardial infarction or uncontrolled angina within months History of a stroke, myocardial infarction, or unstable angina in the previous months Has a medical history of myocardial infarction or unstable angina History of myocardial infarction within months or unstable angina within the past months. Myocardial infarction or unstable angina less than months before registration History of myocardial infarction or unstable angina within months prior to Day Must not have a history of myocardial infarction, severe or unstable angina, or peripheral vascular disease Myocardial infarction or unstable angina < months prior to registration History of myocardial infarction or unstable angina within months prior to study enrollment history within the last months of symptomatic congestive heart failure, myocardial infarction, or unstable angina Unstable angina and/or myocardial infarction within months prior to screening History of myocardial infarction (within months) or unstable angina (within months) prior to study enrolment. Patients are excluded if they have a history of myocardial infarction or unstable angina within months prior to randomization History of myocardial infarction, severe/unstable angina, or symptomatic congestive heart failure, within the months prior to study drug administration Unstable angina or new-onset angina (begun within the last months), or myocardial infarction within the months prior to enrollment Myocardial infarction or unstable angina within months prior to registration. Diagnosis of unstable angina or myocardial infarction within months of study entry Patients with a history of stroke, myocardial infarction, or unstable angina within months prior to registration are not eligible Myocardial infarction or unstable angina within months prior to Day of the study. Myocardial infarction or unstable angina within months prior to the first dose of study drug. Recent history of myocardial infarct (less than months) or history of active angina or arrhythmia Patients with a history of the following within =< months of study entry are not eligible:\r\n* Arterial thromboembolic events\r\n* Unstable angina\r\n* Myocardial Infarction History of myocardial infarction or unstable angina within months prior to study Day History of myocardial infarction or unstable angina within months prior to day History of myocardial infarction or unstable angina within months prior to day - Patients with myocardial infarction or unstable angina =< months prior to registration History of myocardial infarction or unstable angina within months prior to day History of myocardial infarction or unstable angina within months prior to enrollment. Myocardial infarction or uncontrolled angina within months; History of myocardial infarction or unstable angina within months prior to Day Active coronary artery disease, unstable or newly diagnosed angina or myocardial infarction less than months prior to first study drug administration Has a medical history of myocardial infarction or unstable angina. History of myocardial infarction or unstable angina within months prior to first study treatment unstable angina or myocardial infarction within months of enrollment. Myocardial infarction or unstable angina < months prior to enrollment History of unstable angina or myocardial infarction within months prior to Day or ischemic heart disease. Myocardial infarction, severe angina, or unstable angina within months prior to administration of first dose of study drug History of myocardial infarction within months prior to Cycle , Day , or history of unstable angina History of myocardial infarction or unstable angina within months of enrollment Unstable angina or myocardial infarction within months prior to first dose History of myocardial infarction, severe or unstable angina, peripheral vascular disease or familial QTc prolongation. History of myocardial infarction or uncontrolled angina within months prior to administration of study drug Myocardial infarction or unstable angina within months prior to the first administration of study drug; Unstable angina or myocardial infarction within months of enrolment, History of myocardial infarction within months before Cycle , Day , or history of unstable angina Myocardial infarction or unstable angina within months of day prior to registration Significant cardiovascular diseases (i.e., hypertension not controlled by medical therapy, unstable angina, history of myocardial infarction within the past months, History of a stroke, myocardial infarction, or unstable angina in the previous months History of myocardial infarction or unstable angina within months prior to day Myocardial infarction or unstable angina within or month of starting nintedanib treatment, respectively History of unstable angina or myocardial infarction in the last week History of unstable angina or myocardial infarction month prior to study enrollment History of myocardial infarction or unstable angina within months prior to day No unstable angina, regular use of nitroglycerin for exertional angina, or myocardial infarction (MI) within the last months History of unstable angina or myocardial infarction month prior to study enrollment History of unstable angina or myocardial infarction month prior to study enrollment Patients with myocardial infarction or unstable angina < months prior to starting study