Patients with nasopharyngeal carcinoma, salivary gland or skin primaries Nasopharyngeal carcinoma Patient has disease of nasopharyngeal carcinoma histology Nasopharyngeal or sinonasal carcinoma Disease at the nasopharyngeal, sinus, oral cavity, or other sub-site not specified EBV (+) nasopharyngeal carcinoma in the protocol treated tumor Primary nasopharyngeal carcinoma Documentation that the patient is a candidate for chemoradiation of their nasopharyngeal cancer by one of the study investigators Primary tumor of the nasopharynx (nasopharyngeal carcinoma) Nasopharyngeal primary site Primary nasopharyngeal carcinoma Patients with nasopharyngeal, paranasal sinus, skin, or unknown primary site disease Patients with nasopharyngeal carcinoma Patients with nasopharyngeal carcinoma Patients with nasopharyngeal carcinoma, skin squamous cell carcinoma (SCC), and salivary gland carcinomas are not eligible Prior nasopharyngeal cancer, salivary gland or sinus tumors. Epstein-Barr virus-associated nasopharyngeal carcinoma basket:\r\n* None Patients with nasopharyngeal carcinoma are not eligible Nasopharyngeal primary site, if WHO type II or III (non-keratinizing) AT THE TIME OF PROCUREMENT: Nasopharyngeal carcinoma in first or subsequent relapse or with primary refractory disease AT THE TIME OF INFUSION: Nasopharyngeal carcinoma in first or subsequent relapse or with primary refractory disease Nasopharyngeal, salivary gland, lip or sinonasal carcinoma Nasopharyngeal Carcinoma Nasopharyngeal carcinoma Nasopharyngeal cancer Nasopharyngeal strictures Nasopharyngeal cancer Eligible disease(s)/stage(s): nasopharyngeal carcinoma, paranasal sinus cancers/any stage Patients with paranasal sinus or nasopharyngeal carcinoma who are about to undergo radiation therapy; patients with paranasal sinus or nasopharyngeal carcinoma who have completed radiation therapy - months prior to enrollment who then show olfactory loss on a screening test (University of Pennsylvania Smell Identification Test [UPSIT] score of or or lower out of , depending on female/male); both those patients undergoing chemotherapy and those who did not will be eligible, and this factor will be assessed as a possible confounder/contributor in a multi-regression analysis Patients with sinusitis, obstruction of nasal passages, nasopharyngeal cancer, paranasal sinus malignancies, or any conditions in the nasopharyngeal anatomical area that may affect the absorption of fentanyl nasal spray Patient with nasopharyngeal carcinoma Nasal, paranasal sinus, or nasopharyngeal carcinoma, aside from WHO Type I and II (keratinizing, non-EBV positive) nasopharyngeal carcinoma which will be allowed. All nasopharyngeal, paranasal sinus, salivary cancer, and thyroid malignancies Primary nasopharyngeal carcinoma.