Weight ? kg Patient with a BMI > kg/m and weighing at least kg Weight ? kg At least kg ELIGIBILITY FOR SCREENING: Weighs at least kg Patient weight >= kg; patients >= kg with MUDs must be discussed with the principal investigator Must be >= kg STRATUM B: Must meet the following weight and body surface area (BSA) restrictions:\r\n* For enrollment on dose level A, must have a weight >= kg and < kg\r\n* For enrollment on dose level B must have a weight >= kg and BSA >= .m^\r\n* For enrollment on dose level , must have a weight >= kg and BSA >= .m^\r\n* For enrollment on dose level , must have a weight >= kg and BSA >= .m^\r\n* For enrollment on dose levels or A, must have a weight >= kg \r\n* For enrollment on dose levels B or , must have a weight >= kg and =< kg Weight < kg > kg CELL PROCUREMENT: Pediatric subjects (weight must be >= kg) Weight over kg Patients must be >= kg Weight > kg (required for flat dose-based administration of study agents) Less than or equal to kg PRIOR TO CELL PROCUREMENT: For pediatric subjects (weight must be ? kg) Weight ? kg ( lb) Patients with a weight of < kg Patients weighing less than Kg Weight > kg Weight > kg ( lb) and ? kg ( lb); if between and years of age must weigh >= kg ( lb) Patients must be >= kg Must be - years of age and at least kg Weighs at least kg Clearance to be calculated using Cockcroft formula: Males: . x ( - age) x weight (kg) - serum creatinine (?mol/l) ; Females: . x ( - age) x weight (kg) - serum creatinine (?mol/l) Weight >= kg Weight < kg At least kg ( - age) x (weight in kg) x (. if female)/ x (serum creatinine in mg/dL) Patients weighing less than kg Patient must be > kg Age and above and > kg. Weight < kg Subjects with a body weight > kg (for Cohorts dosing mg/kg of ALXN and higher only). Weight of at least kg. Weight between kg and kg Weight >= kg Weight ?rd percentile for age and gender (and ?. kg) > kg at the time of apheresis; patients between - kg. must be approved by the apheresis unit prior to enrollment on protocol Weight ? kg. Weight >= kg Patients weighing < kg Weight > kg ( lbs) Patient weight >= kg Patients < kg or > kg, based on literature regarding accuracy of FloTrac Overweight or obese (> kg/m^) Patients whose BMI falls outside the eligible range (< kg/m^ or > kg/m^) Patients weighing < kg Weight > kg weight of less than or equal to kg (for sites using cefuroxime only). Weight between kg to kg Patient weight at least . kg. Normal weight (BMI < . kg/m^) Body weight between kg ( lb) and kg ( lb), inclusive Patient weighs > kg Unexplained change in weight (> . kg) within the past months