Prior histone deacetylase (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid for the treatment of cancer is allowed Prior anti-cancer treatment with MLN (ixazomib), histone deacetylase (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid Prior histone deacetylases (HDAC) inhibitor, deacetylase (DAC) inhibitor, heat shock protein (Hsp) inhibitor or valproic acid for the treatment of cancer Prior histone deacetylase (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid for the treatment of cancer Prior HDAC, deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid for treatment of cancer Prior therapy with a known heat shock protein (HSP) inhibitor RECURRENT/ PROGRESSIVE DIPG (STRATUM ): Patients have had prior histone deacetylase (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors for the treatment of their DIPG Prior histone deacetylases (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid for the treatment of cancer Patients must not have had any prior exposure to heat shock protein (HSP) inhibitors (such as IPI- or ganetespib) or non-crizotinib ALK inhibitors (such as AP or LDK) Prior therapy with heat shock protein (HSP)- inhibitors Histone deacetylase (HDAC), deacetylase (DAC), heat shock protein (HSP) inhibitors or valproic acid for the treatment of cancer within days; only Food and Drug Administration (FDA) approved drug are vorinostat and romidepsin the rest are considered investigational and are not allowed