Patients with advanced malignant hepatic tumors.
Must not have an advanced malignant hepatic tumor
Patients with advanced malignant solid tumors are excluded
Tumors of low malignant potential
Presence of advanced malignant hepatic tumors.
Primary brain malignant tumors
Patients with metastatic malignant solid tumors who received treatment in the past  months are excluded
Patients with advanced malignant solid tumors are excluded
Patients with advanced malignant hepatic tumors (metastasis)
Patients with advanced malignant hepatic tumors
Patients with advanced malignant hepatic tumors
Patients with advanced malignant solid tumors
Known advanced malignant hepatic tumors
Presence of GI disease, malignant tumors or other conditions known to interfere with ADME
Patients with advanced malignant hepatic tumors (liver metastases that replace more than % of the liver parenchyma)
Diffuse tumors or multiple malignant tumors in the breast.