Acute or chronic liver or renal disease Acute or chronic uncontrolled renal disease, pancreatitis or liver disease (with exception of patients with Gilbert's Syndrome, asymptomatic gall stones, liver metastases, or stable chronic liver disease per investigator assessment) Acute or chronic liver disease or severe renal disease considered unrelated to the cancer Patients with acute or chronic liver, renal disease or pancreatitis Patients with acute or chronic liver, renal disease or pancreatitis Acute or chronic liver disease or severe renal disease considered unrelated to the cancer Patients with acute or chronic liver, renal, lung disease or pancreatitis Patients with acute or chronic liver, renal disease or pancreatitis Acute or chronic liver, pancreatic or severe renal disease Acute or chronic liver or severe renal disease Acute or chronic liver disease or severe renal disease considered unrelated to the cancer Patients with acute or chronic liver, renal disease or pancreatitis Acute or chronic liver or pancreatic disease. Patients with acute or chronic liver, renal disease or pancreatitis Acute or chronic liver disease or severe renal disease considered unrelated to the cancer Acute or chronic liver disease or severe renal disease considered unrelated to the cancer Acute or chronic renal disease or pancreatitis Presence of acute or chronic liver, renal disease, or pancreatitis Patients with acute or chronic liver, renal disease or pancreatitis Patients with acute or chronic liver, renal disease, or pancreatitis liver, pancreatic or severe renal disease unrelated to disease under study