Willingness and ability to consent (and assent if under age ) for self to participate in study Willingness and ability to consent to participate in study Able to understand the study procedures and agree to participate in the study by providing written informed consent Is able to provide written informed consent (in English) to participate in the study and able to understand the procedures and study requirements Willingness and ability to consent for self to participate in study Must have voluntarily agreed to participate and have signed the informed consent, and are willing to complete all study procedures. Provide written, informed consent to participate in the study and follow the study procedures Patients must give documented informed consent to participate in this study Provide written, informed consent to participate in the study and follow the study procedures Willingness and ability to consent for self to participate in study Subjects must give written informed consent to participate in this trial Patients must agree to participate and be able to understand and provide informed consent to participate in the trial Subjects who provide written informed consent to participate in the study Patients must give documented informed consent to participate in this study Patient should be able to provide signed written informed consent; before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel; written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelines Willing and able to consent for self to participate in study Able to give written informed consent to participate in the study Part : be able to understand the description of the study and give written informed consent Signed informed consent to participate in the study, including participation in the expansion cohort after safety of enzalutamide and gemcitabine and cisplatin have been established, must be obtained from patients after they have been fully informed of the nature and potential risks by the investigator (or his/her designee) with the aid of written information Before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel Patients must give documented informed consent to participate in this study Patients must provide verbal and written informed consent to participate in the study Provide written, informed consent to participate in the study and follow the study procedures Patient is willing to participate in the study and has signed the study informed consent Written informed consent to participate in this study before the performance of any study-related procedure Willingness and ability to consent for self to participate in study Voluntary written informed consent of the patient (both to participate in the study and to provide biopsy samples) obtained before any study-specific procedure. Written informed consent to participate in this study Following receipt of verbal and written information about the study, patients must provide signed informed consent before any study-related activity is carried out. Provide written, informed consent to participate in the study and follow the study procedures Be able to understand the study procedures, agree to participate in the study program, and voluntarily provide written Informed Consent Signed informed consent to participate in the study must be obtained from patients after they have been fully informed of the nature and potential risks by the investigator (or his/her designee) with the aid of written information Subjects must give written informed consent to participate in this trial Patients must provide verbal and written informed consent to participate in the study Provide written, informed consent to participate in the study and follow the study procedures Able to participate in the informed consent process Patient should be able to provide signed written informed consent:\r\n* Before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel\r\n* Written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelines Before any study procedures are performed, subjects (or their legally acceptable representatives) will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel Signed informed consent to participate in the study must be obtained from patients after they have been fully informed of the nature and potential risks by the investigator (or his/her designee) with the aid of written information Signed Written Informed Consent\r\n* Before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel\r\n* Written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelines Patients must give documented informed consent to participate in this study Patient has been informed about the nature of the study, and has agreed to participate in the study, and signed the informed consent form prior to participation in any study-related activities Patient has been informed about the nature of the study and has agreed to participate in the study and signed the informed consent form prior to participation in any study-related activities Subjects must give written informed consent to participate in this trial Written informed consent to participate in this study before the performance of any study-related procedure Following receipt of verbal and written information about the study, patients must provide signed informed consent before any study-related activity is carried out. Eligible to give informed consent to participate in the study. PART I: Participants who have no language barrier, are cooperative, and can give informed consent before entering the study after being informed of the medications and procedures to be used in this study may participate PART II: Participants who have no language barrier, are cooperative, and can give informed consent before entering the study after being informed of the medications and procedures to be used in this study may participate Patients must be female, be ? years of age, be able to understand the study procedures, and agree to participate in the study by providing written informed consent. Patients must be able to render informed consent and must consent to participate in the trial Willing to consent to randomization and able to participate in the study Subject is able to read, understand, and sign a written Informed Consent to participate in the study. Patients that consent to participate Consent to the study; and Significant psychiatric or other co-morbid disease, which the treating clinician believes prohibits the patients ability to participate in the informed consent procedures All subjects must have the ability to understand and the willingness to participate in the informed consent process, although a waiver of written informed consent is obtained for this study Patients will have provided informed consent to participate, documented by their signature on the study consent form All patients to give written informed consent to participate Be able to understand the description of the study and give written informed consent Willing to consent to participate Voluntarily agree to participate and read the informed consent documents Subjects consent to participate in the trial Patients must give written informed consent to participate in this study before the performance of any study-related procedure. Able to fully understand and participate in the informed consent process Unwilling or unable to provide informed consent; only individuals (aged or over) who can understand and give informed consent will be approached to participate in this study; individuals who are considered to be mentally disabled will not be recruited for this study; all subjects must understand and be able to give informed consent; we will not be using specific methods to assess decisional capacity; economically disadvantaged persons will not be vulnerable to undue influence, as this study offers no compensation; all individuals will be told that their choice regarding study participation will in no way change their access to clinical care; this should negate any undue influence or coercion; children, fetuses, neonates, or prisoners\r\nare not included in this research study; the menopausal status of the study participant will be reviewed during the screening process by examining the patients chart, women of childbearing potential will have a serum or urine pregnancy test at the time of screening Only individuals (aged or over) who can understand and give informed consent will be eligible to participate in this study Only individuals who can understand and give informed consent will be eligible to participate in this study Able to give written informed consent to participate in the study Patients will have provided informed consent to participate, documented by their signature on the study consent form Patients will have provided informed consent to participate, documented by their signature on the study consent form Patient having provided his/her written informed consent to participate in the trial prior to any study-related procedure being conducted Participant must be able to understand and give consent to participate in the study Willingness and ability to consent for self to participate in study