Patients with known hypersensitivity to perflutren Patients with known or suspected hypersensitivity to perflutren History of hypersensitivity to Definity (perflutren lipid microsphere) or Lumason Known hypersensitivity to sulfur hexafluoride or to any component of perflutren lipid (Definity) Known hypersensitivity to any component of perflutren lipid (Definity) Hypersensitivity to perflutren Known hypersensitivity to perflutren (if the patient has been exposed to perflutren in the past and had an allergic reaction) Women with known cardiac shunt, pulmonary hypertension or hypersensitivity to perflutren agent Patients with known or suspected hypersensitivity to perflutren Patients with any known hypersensitivity to perflutren agent Patients with known hypersensitivity to perflutren Patients with known hypersensitivity to perflutren Known or suspected: hypersensitivity to perflutren, blood, blood products or albumin Known or suspected: hypersensitivity to a prior perflutren protein-type A microspheres (OPTISON) administration