Use of any herbal remedy (e.g. St. Johns wort [hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns Wort [Hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum]) Use of regular phenytoin, carbamazepine, hypericum perforatum (also known as St. Johns wort) or rifampin Use of any herbal remedy (e.g. St. John wort [Hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum]) Patients taking herbal remedies (e.g., St. John's Wort [Hypericum perforatum]) who cannot interrupt therapy from the time the C- consent is signed through days after the last dose of study therapy. Use of any herbal remedy (eg, St. John's wort [Hypericum perforatum]) Note: Granulocyte colony-stimulating factor (G-CSF) and other hematopoietic growth factors may be used in the management of acute toxicity, such as febrile neutropenia, when clinically indicated or at the investigator's discretion. However, they may not be substituted for a required dose reduction. Subjects are permitted to take chronic erythropoietin. Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum]) Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum])