Concurrent diagnosis of invasive or microinvasive breast cancer in either breast Current diagnosis of bilateral breast cancer History of radiotherapy for current breast cancer diagnosis Diagnosis of breast malignancy Subjects must not have received any other breast cancer-specific therapy for the current breast cancer diagnosis prior to registration Patients should have a life expectancy of at least years, excluding their diagnosis of breast cancer; (comorbid conditions should be taken into consideration, but not the diagnosis of breast cancer) diagnosis of HR+, HER+ breast cancer (BC) Proven diagnosis of metastatic breast cancer (MBC). Confirmed diagnosis of HR+/HER- breast cancer History of invasive breast cancer prior to the current diagnosis Have a diagnosis of HR+, HER- breast cancer. Have a diagnosis of HR+, HER- breast cancer Current diagnosis of bilateral breast cancer Current diagnosis of any other active or clinically significant non-breast cancer Have a diagnosis of breast cancer and be chemotherapy naive; NOTE: prior methotrexate for non-cancerous conditions is allowed Post-menopausal patients at breast cancer (BC) diagnosis, as determined locally Diagnosis of other active malignancy; prior treated malignancies in addition to breast cancer are acceptable Ever had a diagnosis of invasive or microinvasive breast cancer Has a breast cancer recurrence, metastasis, or another interval cancer diagnosis following the breast cancer (excluding non-melanoma skin cancer) New breast cancer diagnosis Recent diagnosis of breast cancer with pending surgery as primary treatment for breast cancer Confirmed first diagnosis of stage IV breast cancer or a recurrent diagnosis of metastatic breast cancer (MBC) (i.e., spread to distant organs), any time since diagnosis Patient must be an Asian American who has had a breast cancer diagnosis in the past years Primary diagnosis of breast cancer (initial or recurrence) within the last two years Have a diagnosis of stage I-III female breast cancer or colorectal cancer within the past years; bilateral or multiple primary breast cancers are permitted; individuals who have had more than one type of cancer (e.g., both breast and melanoma) are permitted as long as the breast (or colorectal) diagnosis meets the other criteria and primary treatment for any cancer is not ongoing YOUNG BREAST CANCER SURVIVORS (YBCS): Breast cancer (Stages -III) diagnosis YBCS: Breast cancer diagnosis age ? years Patients who have a diagnosis of breast cancer Patients with a recurrent breast cancer diagnosis Have a previous diagnosis of breast cancer Histologically confirmed stage I, II or III breast cancer (if the patient has had more than one breast cancer diagnosis, then the most recent diagnosis) Primary diagnosis of breast cancer within the last three years Diagnosis of metastatic breast cancer Diagnosis of recurrent breast cancer Diagnosis of breast cancer with adjuvant chemotherapy treatment Diagnosis of breast cancer Diagnosis of HER-positive breast cancer History of a diagnosis of breast cancer Breast cancer diagnosis within past years Have a confirmed diagnosis of breast cancer; participants can have had more than one primary cancer diagnosis in the past Patients with known diagnosis of breast cancer Have a prior diagnosis of T or T breast cancer diagnosed within the last years History of prior breast cancer treated within the past two years; patients completing all breast cancer-specific treatment over two years prior to the current diagnosis are eligible COHORT B: No prior diagnosis of breast cancer but at high risk for development of breast cancer and participating in HSC Diagnosis of breast cancer Previous history or current diagnosis of breast cancer Patients with a previous diagnosis of invasive breast cancer who are less than years from diagnosis Life expectancy of at least years, excluding diagnosis of breast cancer (comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration) New diagnosis of breast cancer New diagnosis if a previous breast cancer patient with negative surgical margins Pathologic diagnosis of invasive breast cancer or high suspicion of breast cancer based on imaging with a suspicious lesion found in the breast and recommended for biopsy or have a confirmed diagnosis of cancer; Women who have undergone open surgical (excisional) biopsy for breast cancer diagnosis Patients must have a current diagnosis of sarcoma, lymphoma, or HER(-) breast cancer Patients with a prior breast cancer diagnosis Patients must have a current diagnosis of breast cancer, non-small cell lung cancer, or colorectal cancer; the current diagnosis may be an initial diagnosis or recurrence and/or progression of previously diagnosed disease; cancer may be metastatic or non-metastatic Diagnosis of invasive breast cancer Pregnant at the time of diagnosis of their breast cancer. Diagnosis of primary breast cancer. Confirmed current or past diagnosis of invasive breast cancer