Patients must not have any unresolved wounds from previous surgery No unhealed wounds, ulcers or bone fractures Have clinically significant dermatological disorders (e.g., eczema, psoriasis, or any unhealed skin wounds or ulcers) as assessed by the principal investigator during screening and during the study Non-healing wounds on any part of the body. Subjects with delayed healing of wounds, ulcers, and/or bone fractures Patients with non-healing surgical incisions or wounds on the scalp Has a known history of non-healing wounds or ulcers, or bone re-fractures within months of fracture Impaired wound healing capacity defined as skin/decubitus ulcers, chronic leg ulcers, known gastric ulcers, or unhealed incisions Unhealed sunburn. Patients with unhealed surgical wounds for more than days Patients with unhealed surgical wounds for more than days Patients with unhealed surgical wounds for more than days Subjects with delayed healing of wounds, ulcers, and/or bone fractures Patients with non-healing surgical wounds; patients must be at least two weeks from a major surgical procedure, and surgical wounds must be completely healed Patients with non-healed wounds. Non-healing wounds on any part of the body. Has not undergone any major surgical procedures for at least weeks, with full healing of all surgical wounds No serious, non-healing wounds or ulcers Evidence of nonhealing wounds, ulcers, or bone fractures within days prior to study entry. Patients with clinically significant dermatological disorders, e.g., eczema or psoriasis, as judged by the principal investigator, or any unhealed skin wounds or ulcers Patients with serious non-healing wounds, ulcers, or bone fractures Open wounds or unhealed fractures within days of starting study treatment Has a history of non-healing wounds or ulcers, or bone refractures within months of fracture Patients with unhealed surgical wounds for more than days Patients with a history of non-healing wounds or ulcers, or bone refractures within months of fracture Surgical or other non-healing wounds, other than KS ulcers Patients with unhealed surgical wounds for more than days History of non-healing wounds or ulcers. Recent major surgery or trauma, unhealing/open wounds. Serious non-healing wounds or ulcers at the time of registration The subject has a history of delayed healing/open wounds or diabetic ulcers. Incomplete recovery or incomplete healing of wounds from previous surgery Unhealed wounds (including active peptic ulcers) Patients with unhealed wounds for more than days Incomplete healing from wounds from prior surgery Open or unhealed wounds or ulcers in the oral cavity Incomplete recovery or incomplete healing of wounds from previous surgery, as determined by treating Investigator Presence of unhealed surgical wounds in chest or breast region and/or breast infection No open breast or chest wounds Open wounds or unhealed fractures within days of starting study treatment