[c09aa8]: / clusters / 9knumclustersv2 / clust_2510.txt

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Must have alanine transaminase (ALT) ? institutional upper limit of normal (ULN) [? ULN in presence of liver metastases] within days prior to randomization.
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN) or =< x ULN with metastatic liver disease within days prior to registration.
Alanine transaminase (ALT) < .x the upper limit of normal (ULN)
aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) ? times the upper limit of normal (ULN)
Hepatic: aspartate transaminase (AST)/alanine transaminase (ALT) ?. x upper limit of normal (ULN); total or conjugated bilirubin ?. x ULN
Alanine transaminase (ALT)/aspartate transaminase (AST) ?. x upper limit of normal (ULN)
Serum aspartate transaminase (AST) or alanine transaminase (ALT) =< . x upper limit of normal (ULN); serum aspartate transaminase (AST) or alanine transaminase (ALT) =< is permissible if due to disease
Adequate hepatic function (total bilirubin ? . upper limit of normal [ULN] for the institution; aspartate transaminase (AST) and alanine transaminase (ALT) ? . ULN.
Serum aspartate transaminase (AST) or alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Aspartate transaminase (AST) ? X upper limit of normal
Aspartate transaminase/alanine transaminase (AST/ALT) ? . x upper limit of normal (ULN)
Alanine transaminase (ALT) and aspartate transaminase (AST) within .x upper limit of normal;
Serum aspartate transaminase (AST) or alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Serum alanine transaminase (ALT) and/or aspartate transaminase (AST) values < x the upper limit of normal (ULN) of the local laboratory reference range
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) < . upper limit of normal (ULN), or AST and ALT < ULN if liver function abnormalities are due to underlying malignancy.
Aspartic transaminase (AST) =< . x upper limit of normal (ULN).
Alanine transaminase (ALT) =< . x upper normal limit (ULN) (=< x ULN for subjects with documented metastatic disease to the liver).
Serum aspartate transaminase or alanine transaminase =< . x upper limit of normal (ULN)
Serum aspartate transaminase (AST) or alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Serum aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) ?. times the upper limit of normal (ULN); and
Serum aspartate transaminase (AST) and alanine transaminase (ALT) less than . times the upper limits of normal
Aspartate transaminase (AST) and alanine transaminase (ALT) ?. times the upper limit of normal (ULN); and
Alanine transaminase (ALT) or aspartate transaminase (AST) >= . x the upper limit of normal (ULN)
Aspartate Transaminase (AST) and alanine transaminase (ALT) =< . x institutional upper limit of normal (ULN) unless liver metastases are present, in which case it must be =< x ULN
Adequate renal and hepatic function (creatinine ? . mg/dl, bilirubin ? . mg/dl, aspartate transaminase (AST) and alanine transaminase (ALT) ? X upper limit of normal range).
Serum alanine transferase (ALT) and aspartate transaminase (AST) < the upper limit of normal (ULN); < ULN if there is liver involvement secondary to the tumor
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) ? . x upper limit of normal (ULN) with alkaline phosphatase ? . x ULN, or AST and ALT ? x ULN if liver function abnormalities are due to liver metastases
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) =< x upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . times the upper limit of normal ([ULN]; or . times the ULN in the setting of liver metastases)
Aspartate transaminase (AST) =< . x upper limit of normal (ULN)
Aspartate transaminase (AST)/alanine transaminase (ALT) =< . upper limit of normal (ULN)
Serum aspartate transaminase (AST) and alanine transaminase (ALT) =< . x institutional upper limit of normal (ULN)
Aspartate Transaminase (AST) / Alanine Transaminase (ALT) ? times institutional upper limit of normal (except in patients with leukemic infiltration of liver)
Has the following laboratory parameters within days before baseline (CD):Serum creatinine ? mg/dL; Total bilirubin ?. mg/dL; Alanine transaminase (ALT) or aspartate transaminase (AST) <.the upper limit of normal (ULN); Left ventricular ejection fraction (LVEF) >%; Forced expiratory volume in second (FEV) >% of predicted.
Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) ? x upper limit of normal (ULN)
Hepatic: bilirubin < . times the upper limit of normal (ULN); alkaline phosphatase (AP), aspartate transaminase (AST), and alanine transaminase (ALT) < . x ULN (AP, AST, and ALT < x ULN is acceptable if the liver has tumor involvement).
Within days of study drug(s) initiation: Alanine transaminase (ALT) and aspartate transaminase (AST) =< . x upper limit of normal (ULN) or =< x ULN if known hepatic metastases.
Serum aspartate transaminase (AST) or alanine transaminase (ALT) less than or equal to . x upper limit of normal (ULN)
Aspartate transaminase (AST) and/or alanine transaminase (ALT) < . x upper normal limit (ULN)
Aspartate transaminase (AST) =< x upper limit of normal (ULN)
Alanine transaminase (ALT) or aspartate transaminase (AST) ? . x the upper limit of normal (ULN).
Baseline alanine transaminase (ALT) or aspartate transaminase (AST) > x upper limit of normal (ULN) without known complications of metastatic liver disease or primary hepatic disease (e.g. Cushings disease and acromegaly studies)
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . times upper limit of normal (ULN) or =< . times the ULN in the setting of liver metastases
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN) for the institution
Hepatic: Aspartate transaminase (AST) / Alanine transaminase (ALT) ? . x upper limit of normal (ULN) (if liver metastases are present, ? x ULN); Total or conjugated bilirubin ? . x ULN
Aspartate transaminase (AST) < . x upper limit of normal (ULN) and alanine transaminase (ALT) ? . ULN.
Aspartate transaminase (AST) level ? . x upper limit of normal (ULN) and alanine transaminase (ALT) ? . upper limit of normal (ULN). For patients with liver metastases, AST ? ULN, and AST ? ULN may be enrolled if agreed upon by the investigator and medical monitor for the sponsor.
Alanine transaminase (ALT)/aspartate transaminase (AST) ? . x upper limit of normal (ULN).
Hepatic: aspartate transaminase (AST) / alanine transaminase (ALT) ? . x upper limit of normal (ULN) (if liver metastases are present, ? x ULN); total or conjugated bilirubin ? . x ULN
Serum aspartate transaminase (AST) or alanine transaminase (ALT) < x upper limit of normal (ULN)
Aspartate transaminase (AST) < . x upper limit of normal (ULN) and alanine transaminase (ALT) ? . upper limit of normal (ULN).
Serum aspartate transaminase (AST) or alanine transaminase (ALT) =< . x upper limit of normal (ULN); if considered related to ASM/MCL =< x ULN
Participant has adequate hepatic function [bilirubin within normal limits (WNL), aspartate transaminase (AST) and alanine transaminase (ALT) ? . times the upper limit of normal (ULN), or ? . times the ULN if the transaminase elevation is due to liver metastases, and alkaline phosphatase ? . times the ULN]
Serum aspartate transaminase (AST) or alanine transaminase (ALT) < x upper limit of normal (ULN)
Aspartate transaminase (AST) =< . x upper limit of normal (ULN) (=< x ULN in patients with liver metastasis)
Aspartate transaminase (AST) and alanine transaminase (ALT) ? x the upper limit of the normal range (ULN) (? x ULN if liver is involved by extramedullary hematopoiesis as judged by the investigator or if related to iron chelator therapy that was started within the prior days)
Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) ? x upper limit of normal (ULN)
Serum aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) < or equal to . upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) ?. upper limit of normal(ULN), or ? . ULN with metastatic liver disease.
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . the upper limit of normal (ULN), or =< the ULN in the presence of known liver metastases
Adequate clinical laboratory values (i.e., plasma creatinine <= . x upper limit of normal (ULN) for the institution, bilirubin <=. x ULN, alanine transaminase (ALT) and aspartate transaminase (AST) <= . x ULN).
serum aspartate transaminase or alanine transaminase > x upper limit of normal (ULN), except in patients with documented liver involvement by lymphoma
Aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limits of normal (ULN)
Aspartate transaminase (AST) less than or equal to . x upper limit of normal, CTCAE v . grade
For Cohorts and : serum aspartate transaminase (AST) or alanine transaminase (ALT) ?. x upper limit of normal (ULN); for Cohort : ALT ?. or AST ?. ULN.
Hepatic: Total conjugated bilirubin ? . x upper limit of normal (ULN); aspartate transaminase (AST) and alanine transaminase (ALT) < x upper limit of normal (ULN) or < x ULN in the setting of liver metastases
Hepatic: Total bilirubin < upper limit of the normal range (ULN); aspartate transaminase (AST) and alanine transaminase (ALT) ? x ULN
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) =< . X upper limit of normal
Total bilirubin ? . x upper limit of the normal range (ULN); aspartate transaminase (AST) and alanine transaminase (ALT) ? x ULN
Adequate hepatic function (total bilirubin ? .x ULN (upper limit of normal) for the institution; AST [aspartate transaminase] and ALT [alanine transaminase] ? x ULN, or ? x ULN if due to liver involvement by tumor).
Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) < . x upper limit of normal (ULN) unless due to disease.
Serum aspartate transaminase (AST) or alanine transaminase (ALT) . x upper limit of normal (ULN) if no demonstrable liver metastases or x ULN in the presence of liver metastases
Hepatic: Aspartate transaminase (AST) / Alanine transaminase (ALT) ? . x upper limit of normal (ULN) (if liver metastases are present, ? x ULN); Total or conjugated bilirubin ? . x ULN
Alanine transaminase (ALT) ? institutional upper limit of normal (ULN) [? ULN in presence of liver metastases] within days prior to randomization.
Serum aspartate transaminase (AST) =< . x upper limit of normal
Serum alanine transaminase (ALT) =< . x upper limit of normal
Serum aspartate transaminase (AST) and alanine transaminase (ALT) < x upper limit of normal (ULN)
Advanced liver disease, including persistent aspartate transaminase (AST), alanine transaminase (ALT), or total bilirubin value > the upper limit of normal, liver biopsy demonstrating cirrhosis, extensive bridging fibrosis, or active hepatitis.
Alanine transaminase (ALT), Aspartate transaminase (AST), or Creatine kinase (CK) greater than times the upper limit of normal
Aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) ? times the upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) ?. the upper limit of normal (ULN)
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) =< . X upper limit of normal
Alanine aminotransferase (ALT) and aspartate transaminase (AST) ?.*upper limit of normal (ULN), and alkaline phosphatase and total bilirubin within normal limits
The participant has adequate hepatic function as defined by a total bilirubin ? . x the upper limit of normal (ULN), and aspartate transaminase (AST) and alanine transaminase (ALT) ? x the ULN (or ? x the ULN in the presence of known liver metastases)
Serum aspartate transaminase (AST) and serum alanine transaminase (ALT) =< . x upper limit of normal (< X upper limit of normal [ULN] for subjects with liver metastasis)
Hepatic: serum bilirubin less than x upper limit of normal for age as per local laboratory) (with the exception of isolated hyperbilirubinemia due to Gilbert's syndrome), alanine transaminase (ALT) and aspartate transaminase (AST) less than x upper limit of normal for age (as per local laboratory)
Aspartate transaminase (AST) =< x upper limit of normal (ULN)
Aspartate transaminase (AST) and alanine transaminase (ALT) levels =< x upper limit of normal (ULN)
Serum aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Serum aspartate transaminase (AST) and alanine transaminase (ALT) =< . x upper limit of normal (ULN)
Total bilirubin ?. times upper limit of normal value (ULN), aspartate transaminase (AST) and alanine transaminase (ALT) ? ULN.
Aspartate transaminase (AST) =< x upper limit of normal (ULN)
Significant liver disease as defined as aspartate transaminase (AST) or alanine transferase (ALT) twice than normal
Aspartate transaminase (AST) and alanine transaminase (ALT) . upper limit of normal (ULN), or ? . ULN with metastatic liver disease
Baseline safety laboratory abnormalities: ANC (absolute neutrophil Count) < cells/mm, platelet count < , cells/mm, hemoglobin < . g/dL, AST (aspartate transaminase) or ALT (alanine transaminase) > x ULN (upper Limit of normal), bilirubin > . x ULN
Aspartate transaminase (AST) =< x upper limit of normal (ULN) (=< x ULN acceptable for pancreatic subjects with known liver metastasis only)
The participant has adequate hepatic function as defined by a total bilirubin less than or equal to x the upper limit of normal (ULN), aspartate transaminase (AST, SGOT) and alanine transaminase (ALT, SGPT) less than or equal to x the ULN (or less than or equal to x the ULN in the presence of known liver metastases).
The participant has adequate hepatic function as defined by a total bilirubin less than or equal to x the upper limit of normal (ULN), aspartate transaminase (AST, SGOT) and alanine transaminase (ALT, SGPT) less than or equal to x the ULN (or less than or equal to x the ULN in the presence of known liver metastases).