Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening period through days after the last dose of protocol therapy Subject is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Is pregnant or breastfeeding or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study treatment. Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study drug. Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the study starting with the screening visit through days after the last dose of pembrolizumab or through days after the last dose of paclitaxel, docetaxel or irinotecan Pregnant or breastfeeding or expecting to conceive or father children from the Screening Visit (Visit ) through days after last dose of study drug Is pregnant or breastfeeding or expecting to conceive or father children starting with the screening visit through days after the last dose of study therapy Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study. Patient is pregnant or breastfeeding, or expecting to conceive children within the projected duration of the study drug or within the day period after the last dose of study drug. Is pregnant or breast feeding or expecting to conceive or father starting from the first dose of study medication, throughout the study period, and for up to days after the last dose of study medication Is pregnant or breast-feeding or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study treatment. Patients may not be pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, from registration through days after the last dose of trial treatment Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study. Pregnant, breastfeeding, or expecting to conceive children within projected duration of study Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study medication Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial through days after the last dose of study medication Is pregnant or breastfeeding, or expecting to conceive or father children while on study drug and for the required duration of contraception after the last dose of study drug. Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial If female, is pregnant, breastfeeding, or expecting to conceive starting with the screening visit through days after the last dose of study drug. Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the Screening visit through days after the last dose of study treatment. Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting from Screening through to days after the last dose of study treatment. Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial Subjects must not be pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the final dose of study medication Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting from the time of consent through days after the last dose of trial treatment Pregnant or breastfeeding, or expecting to conceive within the projected duration of the trial through days after the last dose of study treatment Patients who are pregnant or breastfeeding, or expecting to conceive within the projected duration of the study; lactating patients will be excluded from this study Subject is pregnant or breastfeeding, or expecting to conceive or father a child within the projected duration of the trial participation (from weeks prior to the first dose of study treatment, while participating on the study and through days after the last dose of trial treatment) Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the study Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Is pregnant, breastfeeding, or expecting to conceive or father a child within the projected duration of the study including days following the last dose of study treatment; or Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study. Pregnant, breastfeeding or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of pembrolizumab and up to days after the last dose of chemotherapeutic agents. Patient is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of SOC or days after the last dose of pembrolizumab Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the first dose of study drug through days or longer based on local regulation after the last dose of study drug. Patient is pregnant, breastfeeding, or expecting to conceive children, while receiving study treatment and for days after the last dose of study treatment Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the pre-screening or screening visit through days after the last dose of study drug. Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of study medication Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of pembrolizumab or days after the last dose of chemotherapy treatment. Is pregnant or breastfeeding or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study treatment Pregnant or breastfeeding, or expecting to conceive children within the projected duration of the study Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study drug. Is pregnant or breastfeeding, or expecting to conceive or father children prior to days after the last dose of study medication or through days after last dose of chemotherapeutic agents. Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study drug. Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through - days after the last dose of study drug according to local standard of care Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study Is pregnant or breastfeeding, or expecting to conceive children within the projected duration of the study, starting with the screening visit through days after the last dose of study drug Pregnant or breastfeeding, or expecting to conceive or father children during the study and through days after last dose of pembrolizumab or days after last dose of SOC chemotherapy Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial from screening through days after the last dose of study drug Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial through days after last dose of pembrolizumab or days after last dose of docetaxel Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study medication Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study medication. Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of pembrolizumab or through days after the last dose of paclitaxel. Pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of study medication Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of study medication Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of pembrolizumab or days after the last dose of paclitaxel, docetaxel, or vinflunine Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after the last dose of study medication and up to days after last dose of cisplatin Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study starting with the screening visit through days after the last dose of study treatment through and up to days after last dose of chemotherapeutic agents Is pregnant or breastfeeding, or expecting to conceive children within the projected duration of the study, starting with the screening visit through months after the last dose of study treatment for participants who have received cyclophosphamide, and for months after the last dose of study treatment for participants who have not. Patient is pregnant or breast feeding or expecting to conceive or father children within the projected duration of the study, because of the potential for serious adverse reactions in nursing infants from vorinostat, breast feeding must be discontinued for the duration of therapy with vorinostat Is pregnant or breastfeeding or expecting to conceive or father children within the projected duration of the study Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial. Patient is pregnant, breastfeeding, or expecting to conceive children while receiving study drug or for days after the last dose of study drug. Patient is pregnant, breastfeeding, or expecting to conceive children, while receiving study treatment and for months after the last dose of study treatment Patient is pregnant, breastfeeding, or expecting to conceive children, while receiving study treatment and for months after the last dose of study treatment Pregnant women are excluded from this study; breastfeeding should be discontinued if the mother is treated with MK- (pembrolizumab); patients are excluded from this study if pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days after the last dose of trial treatment Is pregnant or breast feeding or expecting to conceive or father children throughout the study period and for up to days after the last dose of study therapy Is pregnant or expecting to conceive, is breastfeeding, or plans to breastfeed from the time of consent through days after the last dose of study drug Female participants who are pregnant or breastfeeding or expecting to conceive children within the projected duration of the study, starting with the screening visit through days after the last dose of chemotherapy or through days after the last dose of pembrolizumab, whichever is greater. Male participants who are expecting to father children within the projected duration of the study, starting with the screening visit through days after the last dose of chemotherapy. Pregnant or nursing women or subjects expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days after last dose of study drug. Subject is pregnant or breast-feeding, or expecting to conceive or father children within the duration of the trial Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the study, starting with the screening visit through days (or longer as specified by local institutional guidelines) after the last dose of study drug. Is pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through days (for participants receiving pembrolizumab) or days (for participants receiving BV) after the last dose of study drug.