Self-reported ability to walk at least blocks (at any pace) Participant must obtain prior approval from insurance to reimburse for oral temozolomide for the duration of the study or agree to self-pay for oral temozolomide Patients who are HIV positive (by self-report) or have clinical or laboratory features indicative of AIDS. Willing to comply with protocol therapy and required safety monitoring (self-report, pulse oximetry, remote spirometry, labs) Patients who are HIV positive (by self-report) or have clinical or laboratory features indicative of AIDS. Psychiatric illness/social situations that would limit compliance with study requirements including returning for scans, taking oral medication, home monitoring of blood pressure and heart rate, recording side effects in a self-report diary, or becoming pregnant while on study drug As per self report, participant has another sleep disorder provided that it is not adequately treated (e.g., sleep apnea without continuous positive airway pressure [CPAP] treatment) As per self report, heavy drinker (regularly having more than alcoholic beverages per week) As per self report, engaging in night shift work To not obscure cortisol assessment, regular smokers per self report (daily use) will be excluded As per self report significant needle phobia as to prevent participation in acupuncture As per self report, currently engaged in ongoing acupuncture Self-identified Black, African or African American women with proven diagnosis of advanced breast cancer (locoregionally recurrent or metastatic disease), either from the primary or a metastatic site Self-identify as African American/Black, Hispanic (any race), or White non-Hispanic Does not self-identify as African American, Hispanic, or White (non-Hispanic) Self-reported race of either African American or Caucasian Unable to perform self-care during radiation isolation Self-report Timeline Follow-Back (TLFB) indicating current marijuana use >= days/week for >= year Self-report of regular menstrual cycles >= months (female only) Self-reported race of either African American or Caucasian Willing to comply with protocol therapy and required safety monitoring (self-report, pulse oximetry, remote spirometry, labs) The donor has a documented or self-reported history of tuberculosis or recent travel to countries of endemic disease (last weeks) Able to daily self-administer AMG orally as a whole capsule Patients must have Eastern Cooperative Oncology Group (ECOG) performance status of - as below:\r\n* Grade : Up and about, no restriction\r\n* Grade : Ambulatory, no strenuous activity\r\n* Grade : Ambulatory, capable of self-care appropriate for age; up and about > % of time, but unable to carry out any physical activities or attend school\r\n* Grade : Limited self-care only; up and about < % of time\r\n* Grade : Disabled, no self-care; bedridden or confined to chair PART II: ECOG performance status of -\r\n* Grade = Capable of only limited self care, confined to bed or chair more than % of waking hours\r\n* Grade = Completely disabled; cannot carry on any self care; totally confined to bed or chair and in terminal stages of disease Self-reported cognitive problem plus a measured memory deficit (score =< on single trial of eligibility pre-screen Hopkins Verbal Learning Test-Revised [HVLT-R] form C) Self-reported psychotic symptoms in the last days Self-reported current smoker Self-report of being pregnant or lactating Have a pending pain-related Veterans Administration (VA) or social security or worker's compensation (comp) disability claim by self-report Self-reported sexual dysfunction (Derogatis Interview for Sexual Functioning [DISF]-Male [M]-II score =< in the sexual desire domain), and/or fatigue (Functional Assessment of Chronic Illness Therapy [FACIT]-Fatigue [F] score < ), or physical dysfunction (self-reported difficulty in walking a / mile or climbing two flights of stairs, and short physical performance battery score [SPPB] between to ) Zubrod performance status > , or self-reports either not being up and about more than % of waking hours or unable to provide self-care RANDOMIZED INTERVENTION: Score of > on the Distress Thermometer (DT) and indication that this distress is related in some way to the caregiving role per self-report Self-reported shortness of breath (a score of or greater on the Modified Medical Research Council Dyspnea Scale) Willing and able to comply with the protocol, including follow-up visits, examinations as well as having the ability to self-report pain and fatigue using a Patient-Reported Outcome (PRO) instrument Confounding underlying medical illnesses which may cause fatigue (e.g., severe anemia not controlled by medication, per self-report corroborated by medical chart review (e.g., hemoglobin [Hb] < gm/dl)) Self-reported history of bipolar disorder or manic episodes (which is a contra-indication for light treatment) Self-reported sleep duration of hours per night or less Self-reported ability to walk -meters (approximately one city block) without sitting, leaning, or the help of another person or walker A self-reported current practice of yoga or any other mind-body therapy, including but not limited to meditation or hypnosis therapy in the past days prior to study enrollment People who self-report having a severe mental illness Motivated and able to follow the demands of the SHUTi program, to keep sleep records, complete self-report symptom reports and make changes in their sleep schedule, including restricting their sleep Self-reported completion of at least an eighth-grade education PATIENT ONLY: Regularly (self-defined) participation in psychotherapy or a formal cancer support group PATIENT ONLY: Cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team PATIENTS: Regularly (self-defined) participated in a yoga practice in the year prior to diagnosis. PATIENTS: Cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team. Patients who report that they are unable to complete basic functional (e.g., driving, walking) and self-care (e.g., bathing, dressing) activities because of their likely inability to attend the required in-person intervention session Self-report of hospitalization for psychiatric illness within the last two years Participants must self-identify as female; thus only women with breast cancer will be invited to participate in this study Participants must self-identify as Hispanic/Latina Motivated and able to follow the demands of the CBTI-CS program, to keep sleep records, complete self-report symptom reports and make changes in their sleep schedule, including restricting their sleep Reports a fall within the past year OR self-reports that they are concerned about falling As per self-report and/or medical record history of diagnosed neurological illness including seizure disorder, a dementing condition, or other neurological illness (multiple sclerosis, history of cerebrovascular accident, etc.) Participants with untreated depression or anxiety as assessed by self-report and review of medical history As per self-report participants who are pregnant or who are breastfeeding As per self-report participants with pacemakers, intracranial electrodes, implanted defibrillators or any other prosthesis ECOG PS of (capable of limited self-care; confined to a bed or chair > % of waking hours) or (cannot carry on any self-care; totally confined to bed or chair) As per self report or as per medical record starting penile injections as part of the erectile rehabilitation program at MSKCC As per self report, specific injection phobia PHASE : PEER MENTOR ELIGIBILITY: Self-reported primary responsibility for care and complete readiness using the Readiness for Transition Questionnaire PHASE : PATIENT ELIGIBILITY: Currently does not independently self-manage follow-up care according to self-report (i.e., reports low readiness to assume total responsibility for care [score of or out of on overall readiness item OR scores < on any of the -item responsibility scale) using the Readiness for Transition Questionnaire) PHASE B: PEER MENTOR ELIGIBILITY: Self-reported primary responsibility for care and complete readiness using the Readiness for Transition Questionnaire PHASE B: PATIENT ELIGIBILITY: Currently does not independently self-manage follow-up care according to self- report (i.e., reports low readiness to assume total responsibility for care [score of or out of on overall readiness item OR scores < on any of the -item responsibility scale) using the Readiness for Transition Questionnaire) PHASE : PATIENT EXCLUSION CRITERIA: Physician- or self-reported cognitive delay or impairment that would prevent self-management of healthcare PHASE : PATIENT EXCLUSION CRITERIA: Physician- or self-reported cognitive delay or impairment that would prevent self-management of healthcare PHASE A/B: PATIENT EXCLUSION CRITERIA: Physician- or self-reported cognitive delay or impairment that would prevent self-management of healthcare Patient is self-identified as African-American As per self-report, a current caregiver to a patient with any site or stage of cancer If participating in optional biospecimen collection; as per self-report, has medical conditions that affect the immune system and would confound immune evaluation (e.g., autoimmune disorder, inflammatory disease; uncontrolled thyroid disease; active infection; myocardial infarction or stroke in the last months; type I diabetes; acute hepatitis; recent vaccination for viral disease) As per self-report, is a regular smoker (daily use) As per self-report, is a heavy drinker (regularly having more than alcoholic beverages per week for men, for women) As per self-report, engaging in night shift work As per self-report, currently engaged in ongoing psychotherapy PATIENTS AND PARTNERS: Regular (self-defined) participation in psychotherapy or a formal cancer support group Has a self-reported history of diagnosed sleep disorders (e.g., obstructive sleep apnea, insomnia), comorbidities associated with poor sleep or fatigue (e.g., chronic fatigue syndrome), or a job with night shifts Inability to complete pain self-report Self-identify as Latina Patient self-report neuropathy score greater than or equal to on a to numeric scale and/or grade or neuropathy (according to the National Cancer Institute Common Toxicity Criteria point grading scale) Unstable self-reported medical or psychiatric illness (Axis I current or within the last years) that would make it unsafe or impossible to adhere to the study protocol Self-report of >= on the Peripheral Neuropathy Question PATIENTS ONLY: Regularly (self-defined) participated in a yoga practice in the year prior to diagnosis PATIENTS ONLY: Cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team Able to complete the onsite training and home self-care activities for LEF management Patient self-reported ESAS psychological scale score (sum of anxiety and depression scores) between and (and/or) individual anxiety or depression score between and on a to numeric scale, where is the worst possible Current suicide risk or significant intentional self-harm in the last six months sufficient to preclude treatment on an outpatient basis Self-report of a discrepancy between present and optimal level of cognitive, emotional, and/or physical functioning Self-reported inability to walk blocks (at any pace) One or both of the parents will self-identify as Hispanic/Latino, the primary participating parent will be either Spanish speaking, bilingual, or is bilingual but identifies their primary language as English and will live with the child Parent/Caregiver: one or both of the parents will self-identify as Hispanic/Latino, the primary participating parent will be either Spanish speaking, bilingual, or is bilingual but identifies their primary language as English and will live with the child Currently walking =< minutes/day for < days a week (via self-report) Self-identify as Hispanic or Latina Women age years or older who self-identifies as African-American At least years of age who self-identifies as African-American Strong, self-reported history of postoperative nausea and vomiting Participants will self-identify racial/ethnic status as African American (black or of African descent), Hispanic (Latino), or Caucasian (white) Women who self-report to be pregnant\r\n* As this is an observational study, we will not be performing a pregnancy test, participants will be asked if they are or are not pregnant Parent- or self-reported (for participants + years old) physician diagnosis of sarcoma Women who report a change in their body/self-image since diagnosis and wish to improve it; specifically, two screening questions will be used: has your body image or self-image changed in an unwanted way since your cancer diagnosis? (answer must be yes) would you like to be able to do something to improve your body image or self-image? (answer must be yes) answers to both questions must be yes for a woman to be eligible Patients must have normal baseline self-reported taste perception prior to the development of cancer Post-completion of treatment (may be on hormone therapy, such as tamoxifen, or monoclonal antibody, such as Herceptin or pertuzumab) for any type of cancer as confirmed by the medical record at MSKCC, by self-report, or by outside correspondence, including a study checklist signed by a physician for patients outside of MSKCC Cohort participant:\r\n* Has neurocognitive impairment defined as performance on at least one measure of attention, memory, and/ or executive functioning =< th percentile\r\n* Has delayed sleep onset latency defined as self-report of an inability to fall asleep within minutes >= once a week during the past month Cohort participant:\r\n* Is absent of neurocognitive impairment defined as performance > th percentile on all six measures of attention, memory, and executive functioning\r\n* Has delayed sleep onset latency defined as self-report of an inability to fall asleep within minutes >= once a week during the past month Self-identify as Latino Persons with congenital blindness and self-reported acquired blindness (independent of the cause) with no light perception Patients must have normal baseline self-reported taste perception prior to the development of colorectal or pancreatic carcinoma Evidence of any of the following conditions per subject self-report or medical chart review: Self-report of learning disabilities Women who self-identify as Black; Women who do not self-identify as Black; Able to self-administer topical interventions or provide for another person to apply the topical interventions A medical condition, movement or neurological disorder, or medication use that contraindicates participation in moderate intensity exercise (confirmed by self-report on the Health History Questionnaire, and by physician clearance; if in the professional opinion of the Principal Investigator, Dr. Kerri Winters-Stone, contraindications other than those identified by the patient or physician are present, she may consider the participant ineligible) Diagnosis of major depressive episode, acute anxiety disorder, liver or kidney dysfunction (defined by SGOT and creatinine levels . x upper limit of normal) as listed in the patients medical history in the chart within the past year and by self report Breast density will be determined by prior mammography reports, when available, or by radiologist review of prior imaging; all other risk factors used to determine patient eligibility for annual or biennial screening will be determined by subject self-report Males who self-identify as having had or currently having sex with men; both human immunodeficiency virus (HIV)-infected and HIV-uninfected subjects are being enrolled Pregnant women are not eligible as the self-collection device is not recommended for use in this group Women who self-report having received a hysterectomy Phase I: Self-identify as Hispanic/Latino Phase II: Self-identify as Hispanic/Latino Be self-identified as Latino/Hispanic Self-reported consumption of more than alcoholic drinks per day SITE ELIGIBILITY (AS PER SC SELF-REPORT) SITE COORDINATOR (SC) ELIGIBILITY (AS PER SELF-REPORT) PATIENT ELIGIBILITY (AS PER SELF-REPORT) PATIENT (AS PER SELF-REPORT) HISPANIC/LATINOS (H/L): Self-report Hispanic ethnicity (there will be no exclusions based on reported race). WHITE, NON-HISPANIC: Participant whose medical records or self-report indicate any race or ethnicity identification aside from white, non-Hispanic. H/L: Participant whose medical records or self-report indicate an ethnicity aside from Hispanic. Self-identification as Black/African American Is pregnant (self-reported) Born in Mexico or born in the United States (U.S.) but self-describes as Mexican-American; Spanish is her/his primary language Has a minimum of one child between the ages of and who has not received the HPV vaccine and who lives with the parent/guardian as per self-report Self-reported average consumption of > alcoholic drink per week Should self-report \very well\ or \well\ level of English fluency (according to the standard United States [US] census question) Self reports \well\ level of English fluency and indicates a preference for an interpreter Self-identified African American PILOTS I, II AND III: Women who are pregnant (by self-report) Self identifies as American Indian or Alaska native Is a current smoker self defined Self-identified foreign born individuals in China, Korea, and Vietnam Self-identifies as gay or bisexual Self identify as Latina Does not self-identify as Latina For the LBGT cohort study, subjects will be excluded for unwillingness to provide contact information or if they do not self-identify as LGBT in the screener Self-reported Hispanic/Latino ethnicity Subjects with any significant psychological disturbance that, in the opinion of the Investigator, could impair the consent process or ability to complete self-assessment questionnaires. Self-identify as African American FOLLOW-UP ASSESSMENTS: Self-identify as African American Self-reported inability to walk at least blocks (at any pace). Self-reported consumption of more than alcoholic drinks per day Self-identifies as being Hispanic or Latino LHW: self-identified as Filipino, Hmong, or Korean Americans PARTICIPANTS: Self-identified as Filipino, Hmong, or Korean Americans Self-report regular smoking Self report of regular menstrual cycles (female only) Self-identified African-Americans who are literate and fluent in English Willingness to self-report level of oral pain using Visual Analog Scale (VAS) and the Normalcy Diet Scale (NDS) throughout each stomatitis event, as required in the patient diary. At baseline, patient's self-reported oral pain level, using VAS, must be and the normalcy diet scale score should ? Self identified as a smoker Women presenting for mammographic evaluation of an undiagnosed palpable mass found either by self examination and/or examination by referring physician Self-identify as African American or Black Current or former smoker by self-report Antibiotic use within months of study enrollment or during the study by self-report Participant must be a non-Hispanic white or non-Hispanic black (self-reported race) woman to years of age and postmenopausal; postmenopausal will be defined as no menstrual cycle in the past months; women with a hysterectomy but with intact ovaries will be included if aged >= years Self-reported race other than non-Hispanic white or non-Hispanic black Current smoker of >= cigarettes daily, determined by self-report Antibiotic use within months of study enrollment by self-report Patients self-identify as Black, African American, or White and non-Hispanic CLINICIAN: Willingness to be audio-recorded as per self-report PATIENT: Willingness to be audio-recorded as per self-report Eastern Cooperative Oncology Group (ECOG) status of - , or self-reports being up and about more than % of waking hours and able to provide self-care (Arm ) Self-reports hypertension that is not being monitored by a physician and is not being managed with either medication, observation, or lifestyle change (Pre-pilot phase, Arms -) Zubrod performance status > , or self-reports either not being up and about more than % of waking hours or unable to provide self-care (Arms and ) Self-reported prostate cancer diagnosis