Major surgery other than diagnostic surgery, within weeks prior to the first dose of test drug, minor surgery including diagnostic surgery within weeks ( days) excluding central IV port placements and needle aspirate/core biopsies. Radio frequency ablation or transcatheter arterial chemoembolization within weeks prior to the first dose of test drug. Major surgery, other than diagnostic surgery, within weeks prior to Cycle Day , without complete recovery. Major surgery, other than diagnostic surgery, within weeks prior to Cycle Day , without complete recovery. Major surgery, other than diagnostic surgery, within weeks prior to Cycle Day , without complete recovery. Major surgery, other than diagnostic surgery, within weeks prior to Cycle Day , without complete recovery. Major surgery other than diagnostic surgery =< weeks prior to registration Major surgery within days prior to the first drug administration (minimally invasive procedures such as diagnostic biopsies are permitted) Major surgery other than diagnostic surgery within days of Study Day Major surgery other than diagnostic surgery =< weeks prior to registration Major surgery, other than diagnostic surgery, occurring weeks prior to study entry; splenectomy will not be considered an exclusionary major surgery Any major surgery within weeks or a diagnostic procedure (eg incision, needle biopsy) within day of study drug administration Major surgery, other than diagnostic surgery, within weeks prior to day , without complete recovery from the surgical procedure Major surgery other than diagnostic surgery within days of Study Day Major surgery, other than diagnostic surgery, within weeks Major surgery, other than diagnostic surgery, within weeks prior to Day , without complete recovery Major surgery, other than diagnostic surgery, within weeks prior to first dose, without complete recovery. Have major surgery, other than diagnostic surgery, within -weeks prior to Day Major surgery, other than diagnostic surgery, within weeks prior to the first dose of test drug. Patients who have undergone major surgery, excluding diagnostic biopsy, within days (to allow for full recovery) prior to registration Major surgery, other than diagnostic surgery, occurring weeks prior to study entry; splenectomy will not be considered an exclusionary major surgery Subject has had major surgery, other than diagnostic surgery, within weeks prior to treatment in study. Any major surgery within weeks or a diagnostic procedure (e.g. incision, needle biopsy) within day of study drug administration Major surgery, other than diagnostic surgery, within weeks Major surgery, other than diagnostic surgery, within weeks Major surgery, other than diagnostic surgery, within weeks prior to Cycle Day , without complete recovery Major surgery other than diagnostic surgery =< weeks Major surgery, except diagnostic tumor biopsy, within weeks of randomization. Major surgery other than diagnostic surgery within days Major surgery other than diagnostic surgery =< weeks prior to registration