Within days prior to registration: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< x IULN Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . x institutional upper limit of normal (IULN) (or =< x IULN if liver metastases are present) Either alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< x IULN within days prior to sub-study registration (if both ALT and AST are done, both must be =< IULN); for patients with liver metastases, either ALT or AST must be =< x IULN (if both ALT and AST are done, both must be =< x IULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (or < x IULN for patients with known liver metastases) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< x IULN within days prior to registration Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (=< x IULN secondary to lymphoma) within days prior to registration Obtained within days prior to registration: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (or < x IULN for patients with known liver metastases) Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) =< x IULN Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT]) =< . x IULN, =< x IULN for patients with liver metastases Alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< . x IULN, =< x IULN for patients with liver metastases AST/ALT =< . x the IULN or =< x IULN for patients with liver metastases Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< x institutional upper limit of normal (IULN) except for Gilberts disease or when in the opinion of treating physician elevated levels are due to direct involvement of leukemia (e.g., hepatic infiltration or biliary obstruction due to leukemia), in which case ALT and AST may be elevated up to =< x IULN Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . x IULN ALT and AST .- x IULN Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ? . x IULN Alanine aminotransferase (alanine aminotransaminase [ALT]) and aspartate aminotransferase (aspartate aminotransaminase [AST]) ? . x IULN Obtained within days prior to enrollment: aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) =< x institutional upper limit of normal (IULN) without liver mets or =< x IULN with liver metastases Serum aspartate aminotransferases (AST) or alanine aminotransferases (ALT) < . x IULN for patients without liver metastases; for patients with liver metastases AST or ALT < x IULN is allowed Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of less than X IULN Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< x IULN Either alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< x IULN within days prior to Step re-registration (if both ALT and AST are done, both must be =< IULN); for patients with liver metastases, either ALT or AST must be =< x IULN (if both ALT and AST are done, both must be =< x IULN) Either alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< x IULN within days prior to Step re-registration (if both ALT and AST are done, both must be =< IULN); for patients with liver metastases, either ALT or AST must be =< x IULN (if both ALT and AST are done, both must be =< x IULN) Either alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< x IULN within days prior to step re-registration (if both ALT and AST are done, both must be < IULN); for patients with liver metastases, either ALT or AST must be =< x IULN (if both ALT and AST are done, both must be =< x IULN) Obtained within days prior to registration: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (or =< x IULN for patients with known liver metastases) Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) < . x IULN Patients must have aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< x IULN, unless due to lymphoma, within days prior to registration CLINICAL/LABORATORY CRITERIA: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (or =< x IULN for patients with known liver metastases); these results must be obtained within days prior to registration Total bilirubin =< . x IULN or =< . x IULN with normal aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in patients with Gilberts disease Either alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< x IULN within days prior to RE-TREATMENT registration (if both ALT and AST are done, both must be =< IULN); for patients with liver metastases, either ALT or AST must be =< x IULN (if both ALT and AST are done, both must be =< x IULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< . x IULN Within days prior to registration: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN; patients with liver metastases may have AST and ALT of =< . x IULN Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< . X IULN in the absence of liver metastases or =< . x IULN with liver metastasis SGOT (AST) =< . x IULN and SGPT (ALT) =< . x IULN Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< . x IULN OR ALT and AST =< . x IULN for patients with documented hepatic involvement with NHL Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x institutional upper limit of normal (IULN) or =< x IULN if liver metastases are present AST and ALT =< . x IULN or =< x IULN if liver metastases are present within days prior to Step registration Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) =< . institutional upper limit of normal (IULN) (=< x IULN if liver metastases are present) Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< IULN Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< . x IULN (or < x IULN for patients with known liver metastases) Aspartate and alanine aminotransferase =< . x IULN, bilirubin =< .x IULN Total bilirubin =< . x institutional upper limit of normal (IULN) or x IULN with normal alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in patients with Gilberts disease Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both < . x IULN within days prior to registration