Known central nervous system (CNS) leukemia. Clinical evidence of active central nervous system leukemia; Presence of known central nervous system (CNS) leukemia. Known central nervous system (CNS) leukemia Patients with known active uncontrolled central nervous system (CNS) leukemia. Untreated or progressive central nervous system leukemia Patients with known active uncontrolled central nervous system (CNS) leukemia Patients with a known history or prior diagnosis of optic neuritis or other immunologic or inflammatory disease affecting the central nervous system, and unrelated to leukemia or previous leukemia treatment Active central nervous system leukemia Clinically active central nervous system leukemia. Presence of central nervous system involvement of leukemia or a history of primary central nervous system leukemia. Known clinically active central nervous system (CNS) or extramedullary AML, except leukemia cutis. Clinically active central nervous system (CNS) leukemia; Known central nervous system leukemia Known clinically active central nervous system (CNS) leukemia Known clinically active central nervous system(CNS) leukemia Patients with known or suspected central nervous system (CNS) leukemia are not eligible Patients with known central nervous system infiltration with leukemia Subject has clinically active central nervous system leukemia. Patients with known active uncontrolled central nervous system (CNS) leukemia. Subject has clinically active central nervous system leukemia. Patient has central nervous system leukemia Subject has clinically active central nervous system leukemia. Clinical evidence of active central nervous system leukemia at the time of screening Patient must not have known central nervous system (CNS) leukemia Known clinically active central nervous system (CNS) leukemia Patients with known active central nervous system (CNS) leukemia Previous central nervous system leukemia Patients with symptomatic central nervous system (CNS) leukemia or patients with poorly controlled central nervous system leukemia Known active central nervous system (CNS) leukemia. Patients with known active central nervous system (CNS) leukemia will be excluded from this clinical study Known active leukemia of the central nervous system Subject has clinically active central nervous system leukemia Active central nervous system (CNS) leukemia or known chloromatous disease Overt central nervous system manifestations of leukemia at diagnosis Subject has clinically active central nervous system leukemia. Known active or suspected central nervous system (CNS) leukemia. Known active central nervous system (CNS) leukemia.