Estimated creatinine clearance of > ml/min (. mL/s) by the Cockcroft-Gault equation Subject has adequate renal function with an estimated creatinine clearance of ? mL/min by the Cockcroft-Gault equation adjusted for body weight Estimated creatinine clearance (using Cockcroft-Gault equation) must be > mL/min Creatinine clearance >= mL/min/. m^ (as estimated by Cockcroft Gault equation) for subjects with creatinine levels above institutional normal Estimated GFR > ml/min using Cockroft-Gault equation Serum creatinine =< . x ULN or estimated creatinine clearance >= mL/min as calculated using the Cockcroft-Gault (CG) equation. Estimated creatinine clearance (CrCL) using the Cockroft-Gault equation ? mL/min Creatinine ? . x institutional ULN or estimated creatinine clearance of ? mL/min by the Cockcroft-Gault equation or measured creatinine clearance > mL/min Creatinine =< mg/dL or creatinine clearance (as estimated by Cockcroft Gault equation) >= mL/min Alanine aminotransferase (ALT) =< . x ULN; and estimated creatinine clearance (CrCl) of > mL/min, as calculated by the Cockcroft-Gault equation. Creatinine =< . x institutional ULN or estimated creatinine clearance of >= mL/min by the Cockcroft-Gault equation or measured creatinine clearance > mL/min Serum creatinine =< . x ULN or estimated creatinine clearance >= ml/min by Cockcroft-Gault equation Participants must have creatinine clearance estimated using the Cockcroft-Gault equation of >= mL/min, measured within days prior to administration of study treatment\r\n* Note: patients with creatinine clearance between - mL/min either at trial enrollment or during the course of the trial should be monitored every weeks for laboratory assessment and toxicity evaluation Within days of registration: Creatinine >= mL/min estimated using the Cockcroft-Gault equation Estimated creatinine clearance (CrCL) using the Cockcroft-Gault equation >= mL/min Serum creatinine =< . x ULN or estimated creatinine clearance >= mL/min as calculated using the Cockcroft-Gault (CG) equation Creatinine clearance >= ml/min using a hour creatinine clearance or estimated creatinine clearance using the Cockcroft-Gault equation Serum creatinine =< . mg/dL or creatinine clearance >= mL/min as estimated by the Cockcroft-Gault equation Creatinine > . times ULN or an estimated creatinine clearance < mL/minute calculated using the Cockcroft-Gault equation Creatinine =< . mg/dL or creatinine clearance > ml/min (estimated as calculated with Cockcroft-Gault equation) Serum creatinine =< . x ULN or estimated creatinine clearance >= ml/min by Cockcroft-Gault equation Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of >= mL/min within days prior to administration of study treatment. Within days prior to administration of study treatment: Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of ? mL/min Adequate renal function, defined as an estimated creatinine clearance ? mL/min using the Cockcroft-Gault equation Patients should have serum creatinine < . x ULN and estimated glomerular filtration rate (GFR) of > mL/min. If serum creatinine is >= . x ULN, then patient must have creatinine clearance >= mL/min estimated using the Cockcroft-Gault equation. Estimated creatinine clearance (CrCL) using the Cockcroft-Gault equation >= mL/min Creatinine clearance of >= mL/min, estimated or calculated using the Cockcroft-Gault equation. Estimated creatinine clearance > mL/min by Cockcroft-Gault equation Creatinine clearance estimated using the Cockcroft-Gault equation of >= mL/min. Subject has adequate renal function: serum creatinine ? . mg/dL and estimated creatinine clearance of ? mL/min by the Cockcroft-Gault equation Measured within days prior to administration of study treatment: Creatinine clearance estimated using the Cockcroft-Gault equation of >= mL/min Creatinine ?. mg/dL OR estimated creatinine clearance ? mL/min calculated using Cockcroft-Gault equation Estimated creatinine clearance (CrCl) of > mL/min, as calculated by the Cockcroft-Gault equation unless disease related Renal function: serum creatinine ? . mg/dL and estimated creatinine clearance of ? mL/min by the Cockcroft-Gault equation Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of >= mL/min. Serum creatinine within normal institutional limits or estimated creatinine clearance >= mL/min/. m^ by the Cockcroft-Gault equation Creatinine clearance >= ml/min (as estimated by Cockcroft Gault equation) Estimated creatinine clearance by Cockcroft-Gault equation > mL/min Estimated creatinine clearance by Cockcroft-Gault equation > mL/min Creatinine clearance (CLcr) < ml/min (estimated creatinine clearance by the Cockcroft-Gault (C-G) equation) . Within one week of study entry: Creatinine clearance >= ml/min (as estimated by Cockroft Gault equation) Serum creatinine =< . mg/dl OR creatinine clearance >= ml/min (as estimated by Cockroft Gault equation) Creatinine clearance of ? mL/min as estimated by the Cockcroft-Gault equation Serum creatinine =<. mg/dl OR creatinine clearance >= ml/min (as estimated by Cockroft Gault equation) Estimated creatinine clearance (CLcr) ? mL/min as calculated using the Cockcroft-Gault equation Serum creatinine =< . x ULN or estimated creatinine clearance >= mL/min by the Cockcroft-Gault equation - Serum Cr < . x ULN or estimated GFR > ml/min based upon Cockroft-Gault equation Creatinine < . x upper limit of normal (ULN) or estimated creatinine clearance >= mL/min (by the Cockcroft Gault equation) Creatinine < . x upper limit of normal (ULN) or estimated creatinine clearance >= mL/min (by the Cockcroft Gault equation) HEALTHY VOLUNTEER: An estimated creatinine clearance of =< ml/min based on the Cockcroft-Gault equation; an actual creatinine clearance, as determined by a hour urine collection, may be used in place of the Cockcroft-Gault equation; subjects who have an actual or estimated creatinine clearance ml/min may be enrolled at the discretion of the investigator Estimated creatinine clearance >= mL/min (by the Cockcroft Gault equation) Estimated creatinine clearance by the Cockcroft Gault equation >= mL/min - Serum Cr < . x ULN or estimated GFR > ml/min based upon Cockroft-Gault equation Estimated serum creatinine clearance of ? mL/min using the Cockcroft-Gault equation.