Major surgical procedures ? days of beginning study drug, or minor surgical procedures ? days, or has not recovered from major side effects. No waiting required following port-a-cath placement. Major surgical procedures < days from beginning study treatment Major surgical procedures =< days of beginning study treatment, or minor surgical procedures (including ventriculoperitoneal [VP] shunt placement or stereotactic biopsy of the tumor) =< days; no waiting period required following port-a-cath or other central venous access placement Major surgical procedures =< days of beginning study treatment, or minor surgical procedures =< days; no waiting period required following port-a-cath or other central venous access placement Patients who have had minor surgical procedures (with the exception of the placement of porta cath or other central venous access) within days prior to registration Major surgical procedures ? days of beginning study treatment or minor surgical procedures ? days. No waiting is required following port-a-cath placement. Port-a-cath placement: no waiting is required Minor surgical procedures (as defined by the Investigator): postoperative days Nonstudy related surgical procedures prior to IP administration. Non-study related surgical procedures less than or equal to days prior to CK- administration Major surgical procedures =< days prior to D of AZD or minor surgical procedures =< days; no waiting required following port-a-cath placement Major surgery (excluding placement of vascular access) ? days from beginning of the study drug or minor surgical procedures ? days. No waiting is required following implantable port and catheter placement. Major surgical procedures =< days of beginning AZD, or minor surgical procedures =< days; no waiting period required following port-a-cath or other central venous access placement Major surgical procedures =< days of beginning study treatment, or minor surgical procedures =< days. No waiting period required following port-a-cath placement. Patients must have recovered from any surgical procedure before enrolling on this study:\r\n* Patients with a major surgical procedure within days prior to enrollment should be excluded\r\n* Patients with an intermediate surgical procedure within days prior to enrollment should be excluded\r\n* For minor surgical procedures (including Broviac line or infusaport placement), patients should not receive the first planned dose of bevacizumab until the wound is healed and at least days have elapsed\r\n* There should be no anticipation of need for major surgical procedures during the course of the study\r\n** Examples of major, intermediate, or minor surgical procedures:\r\n*** Major procedures: Major craniotomy for tumor resection; organ resection; bowel wall anastomosis; arteriovenous grafts; exploratory laparotomy; thoracotomy\r\n*** Intermediate procedures: Ventriculoperitoneal (VP)-shunt placement; stereotactic brain biopsy\r\n*** Minor procedures: Incision and drainage of superficial skin abscesses; punch biopsy of skin lesions; superficial skin wound suturing; bone marrow aspirate and/or biopsy; fine needle aspirations; Broviac line or infusaport placement; paracentesis or thoracocentesis\r\n* Please note: Lumbar punctures or placement of peripherally inserted central catheter (PICC) lines are not considered minor procedures and may occur at any time prior to or during therapy Major surgical procedures are not allowed ? days prior to FPA administration Major surgical procedures within days of administration of crenolanib (does not include line placement as needed for chemotherapy administration). Major surgical procedures ? days, or minor procedures ? days. Minor surgical procedures such as mediport placement or core biopsies within days of study treatment Major surgical procedures ? days of beginning study drug or minor surgical procedures ? days. No waiting is required following port-a-cath placement. Major surgical procedures within days of Day administration of crenolanib. Minor surgical procedures such as placement of Port-a-Cath, stereotactic biopsy, fine needle aspirations, or core biopsies within days prior to Day Major surgical procedures =< days before beginning study treatment or minor surgical procedures =< day before beginning study treatment; no waiting required after placement of a vascular access device Major surgical procedures ? days of beginning AZD, or minor surgical procedures ? days Major surgical procedures within days of day administration of crenolanib Minor surgical procedures within days prior to study enrollment There should be no anticipation of need for major surgical procedures during the course of the study; examples include:\r\n* Major procedures:\r\n** Organ resection\r\n** Bowel wall anastomosis\r\n** Arteriovenous grafts\r\n** Exploratory laparotomy\r\n** Thoracotomy\r\n* Intermediate procedures: \r\n** Ventriculoperitoneal (VP)-shunt placement\r\n** Stereotactic brain biopsy\r\n** Paracentesis or thoracentesis\r\n* Minor procedures:\r\n** Incision and drainage of superficial skin abscesses\r\n** Punch biopsy of skin lesions\r\n** Superficial skin wound suturing\r\n** Bone marrow aspirate and/or biopsy\r\n** Fine needle aspirations\r\n** Broviac line or infusaport placement\r\n** Note: lumbar punctures or placement of peripherally inserted central catheter (PICC) lines are not considered minor procedures and may occur at any time prior to or during therapy Major surgical procedures =< days of beginning study treatment, or minor surgical procedures =< days (minor procedures done at time of laparoscopy are allowed); no waiting required following port-a-cath placement