Must have creatinine ? . institutional ULN or Creatinine Clearance > ml/min (as calculated by the Cockcroft-Gault equation) within days prior to randomization. Serum creatinine =< . X institutional ULN and creatinine clearance >= ml/min\r\n* NOTE: creatinine clearance must be calculated using the Cockcroft-Gault equation Within less than or equal to days prior to registration: Serum creatinine =< . X institutional ULN and creatinine clearance >= ml/min\r\n* NOTE: Creatinine clearance must be calculated using the Cockcroft-Gault equation Within days of treatment initiation: Measured or calculated creatinine clearance >= mL/min\r\n* Creatinine clearance should be calculated using modified Cockcroft-Gault equation (using ideal body mass [IBM] instead of mass). Direct measured creatinine clearance (i.e. h urine or other method) can be substituted if calculated creatinine clearance is thought to be inadequate per treating physician Serum creatinine =< . mg/dL or calculated creatinine clearance >= mL/min as determined by the Cockcroft-Gault equation Serum creatinine =< . mg/dL or creatinine clearance >= mL/min (calculated by Cockcroft Gault equation) Serum creatinine =< . mg/dL or calculated creatinine clearance >= mL/min as determined by the Cockcroft-Gault equation Creatinine > . times the ULN concurrent with creatinine clearance < mL/min (measured or calculated by the Cockcroft - Gault equation); confirmation of creatinine clearance is only required when creatinine is > . times the ULN. Creatinine ?. x ULN or creatinine clearance ? mL/min as calculated by the Cockcroft-Gault method Serum creatinine calculated creatinine clearance by the method of Cockcroft and Gault (< mL/min) Serum creatinine =< . mg/dL OR creatinine clearance >= mL/min/. m^ for patients with creatinine levels above mg/dL (unless dysfunction is secondary to lymphoma involvement); creatinine clearance (Cr Cl) will be calculated with the use of the -hour creatinine clearance or modified Cockcroft-Gault equation Either serum creatinine > . mg/dL, or creatinine clearance < mL/min calculated by the Cockcroft Gault method, eventually confirmed by measured creatinine clearance (or measured glomerular filtration rate [GFR] using plasma clearance methods) Serum creatinine =< . x ULN or calculated creatinine clearance >= mL/min (Cockcroft Gault equation) Creatinine =< . x ULN, serum creatinine clearance (CL) > ml/min (by the Cockcroft- Gault equation) Serum creatinine =< . mg/dL or calculated creatinine clearance >= mL/min using the Cockcroft-Gault equation Creatinine =< . mg/dL OR calculated creatinine clearance >= mL/min (as calculated by the Cockcroft-Gault method) Creatinine =< . x ULN or creatinine clearance > mL/min (calculated by Cockcroft-Gault method) Or creatinine clearance ? mL/minute for subjects with serum creatinine outside the normal range (calculated using the Cockcroft-Gault equation). Creatinine > . times ULN concurrent with creatinine clearance < ml/min (measured or calculated by Cockcroft and Gault equation); confirmation of creatinine clearance is only required when creatinine is > . times ULN Serum creatinine =< . mg/dL or creatinine clearance greater or equal than cc/min as defined by the Cockcroft-Gault equation Creatinine =< . mg/dL ULN, or calculated creatinine clearance (determined as per Cockcroft-Gault) Serum creatinine =< . x ULN or calculated creatinine clearance (CrCl) >= ml/min based upon the Cockcroft-Gault equation Serum creatinine =< . mg/dL and creatinine clearance >= ml/min; creatinine clearance will be calculated using the Cockcroft-Gault equation Serum creatinine > . times ULN concurrent with creatinine clearance < mL/min (measured or calculated by Cockcroft and Gault equation)confirmation of creatinine clearance is only required when creatinine is > . times ULN Cockcroft-Gault equation: creatinine clearance = ( - age in years) x (wt in kg)) x .) / (serum creatinine in micromol/l) [For women multiply the result of calculation by .]. Serum creatinine =< . mg/dL or creatinine clearance >= mL/min (calculated by Cockcroft Gault equation) =< days prior to registration Serum creatinine =< . mg/dL or creatinine clearance >= mL/min (measured or calculated according to the method of Cockcroft and Gault), within days of day . Creatinine =< . mg/dL, OR calculated creatinine clearance >= mL/min (calculated by the Cockcroft and Gault method) Serum creatinine =< . mg/dL or creatinine clearance >= mL/min (calculated by Cockcroft Gault equation) Creatinine clearance >= mL/min/. m^ for patients with creatinine levels above ULN as calculated by Cockcroft-Gault Serum creatinine =< . g/dL or calculated creatinine clearance >= mL/min (Cockcroft-Gault method) Adequate renal function, with creatinine =< . mg/dl or calculated creatinine clearance >= ml/min by Cockcroft and Gault equation using parameters of age, weight (kg), and baseline serum creatinine (mg/dl) Creatinine: =< . mg/dL, OR calculated creatinine clearance >= mL/min (calculated by the modified Cockcroft and Gault method) Serum creatinine =< . mg/dL OR calculated creatinine clearance (Cockcroft-Gault method) >= mL/minute within days prior to treatment Creatinine must be < . ULN or creatinine clearance must be > mL/min (calculated by Cockcroft and Gault equation) Serum creatinine ? . x ULN or calculated creatinine clearance (using Cockcroft and Gault method) > mL/min) Creatinine =< . mg/dL OR calculated creatinine clearance >= mL/min (as calculated by the Cockcroft-Gault method) Serum creatinine =< . mg/dL or a calculated creatinine clearance of at least mL/min (using the Cockcroft and Gault method) Creatinine >. x ULN concurrent with creatinine clearance < mL/min (measured or calculated by Cockcroft and Gault equation); confirmation of creatinine clearance is only required when creatinine is >. x ULN Serum creatinine =< . mg/dL or a calculated creatinine clearance of at least mL/min (using the Cockcroft and Gault method) =< days prior to enrollment/randomization: Creatinine =< . mg/dL or creatinine clearance >= mL/min calculated by the Cockcroft-Gault method Creatinine < ULN OR calculated creatinine clearance >= mL/min\r\n* Creatinine clearance should be calculated by Cockcroft and Gault method Serum creatinine ? . mg/dL or a calculated creatinine clearance of ? mL/min as determined by the Cockcroft-Gault equation Serum creatinine < . mg/dL or creatinine clearance greater or equal than cc/min as defined by the Cockcroft-Gault equation Creatinine ? . ULN; or, if serum creatinine > . ULN, a measured creatinine clearance must be >mL/min/.m as calculated by the Cockcroft and Gault equation for patient to be eligible. Serum creatinine =< . x ULN or -hour creatinine clearance > mL/min (measured or calculated by Cockcroft-Gault method) Plasma creatinine =< . x ULN or creatinine clearance > mL/min (calculated by Cockcroft-Gault method) Serum creatinine =< . mg/dl and calculated creatinine clearance >= mL/min (using the Cockcroft-Gault equation) Serum creatinine =< mg/dL or a calculated creatinine clearance of >= mL/min (using the Cockcroft and Gault method) Creatinine =< . mg/dL or creatinine clearance >= mL/min calculated by the Cockcroft-Gault method Serum creatinine ? . upper limit of normal (ULN) or calculated creatinine clearance ? mL/min using Cockcroft-Gault equation Creatinine =< . mg/dL, or calculated creatinine clearance (determined as per Cockcroft-Gault) >= mL/min Serum creatinine =< . x ULN or calculated creatinine clearance >= mL/min (using the Cockcroft-Gault equation) Serum creatinine ? . mg/dL or creatinine clearance ? mL/min measured or calculated by Cockcroft-Gault equation. Serum creatinine =< . x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= mL/min as determined by the Cockcroft-Gault equation Creatinine < . x ULN. If >. x ULN, patient may still be eligible if calculated creatinine clearance > mL/min (.mL/s) as calculated by the Cockcroft-Gault method. Serum creatinine < . times institutional upper limit of normal OR calculated creatinine clearance (CrCl) >= mL/min (based upon the Cockcroft-Gault equation)