Patients who have had radiotherapy within days before registration are not eligible; NOTE: if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is limited to a single site, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy =< days prior to registration; NOTE: if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy ? days prior to registration; NOTE: If the involved field is small, days will be considered a sufficient interval between treatment and administration of study drugs Radiotherapy within days before enrollment. If the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy =< days prior to registration; NOTE: If the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy =< days prior to registration; NOTE: If the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small (single nodal area), days will be considered a sufficient interval between treatment and beginning of protocol therapy Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the therapy Radiotherapy within days before randomization; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy =< days prior to registration; Note: If the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment (if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib.) Radiotherapy ? days prior to registration; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy =< days prior to registration\r\n* NOTE: If the involved field is small, days will be considered a sufficient interval between treatment and administration of study drugs Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy within days before first dose of study drug; if the involved field is small, days will be considered a sufficient interval between treatment and study initiation Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy within days prior to the first dose of study drug; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the first dose of the study medications Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the ixazomib Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN (ixazomib citrate) Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of the MLN Radiotherapy within days before enrollment; if the involved field is small, days will be considered a sufficient interval between treatment and administration of MLN