Woman who is pregnant or lactating or has a positive pregnancy test at screening. If a woman has a positive pregnancy test, further evaluation may be conducted to rule out ongoing pregnancy to allow the patient to be eligible Women who are breastfeeding or pregnant as evidenced by a positive pregnancy test within days of first dose. Pregnancy tests for females of childbearing potential are required; must be serum at screening and the post treatment safety assessment visit; a positive urine pregnancy test must be confirmed by a serum pregnancy test and a pelvic ultrasound (US); a pelvic US does not need to be repeated with each cycle unless the treating physician thinks it is necessary to do so Female subjects who have positive serum pregnancy test taken within days of initiation of study treatment. A WOCBP who has a positive urine pregnancy test within hours before the first dose of study treatment. Has a positive pregnancy test within hours before the first dose of study therapy Positive serum pregnancy test A positive pregnancy test will exclude patients from the study in addition to excluding them from receiving standard therapy Women with a positive pregnancy test DONOR: Females with a positive pregnancy test A WOCBP who has a positive serum pregnancy test within hours prior to enrollment on study WOCBP who has a positive urine pregnancy test within hours before the first dose of study treatment Patients who are pregnant or lactating, plan to get pregnant, or have a positive serum pregnancy test prior to randomization. Pregnant or breast-feeding. (While pregnancy is unlikely in view of the disease and previous surgery, subjects whom the investigator considers may be at risk of pregnancy will have a pregnancy [beta-HCG] test and will be using a medically approved contraceptive method). Pregnancy or breastfeeding; women (patients or partners of male patients) of childbearing potential (WOCBP) must practice acceptable methods of birth control to prevent pregnancy; all WOCBP MUST have a negative pregnancy test within weeks prior to registration, and this must be repeated within hours prior to first receiving ruxolitinib; if the pregnancy test is positive, the patient must not receive ruxolitinib and must not be enrolled in the study Women with a positive pregnancy test Women with a positive pregnancy test or lactating. Participants with borderline pregnancy tests at Screening must have a serum pregnancy test ? days later to document continued lack of a positive result. Is pregnant (confirmed by positive serum pregnancy test) or lactating Positive pregnancy test for women of childbearing age Female patients who are lactating or have a positive serum pregnancy test suggestive of pregnancy and not as a tumor marker during the screening period; if pregnancy is tested positive, treating physician will further investigate if the patient is pregnant or not; treating physician may consider repeating the serum beta-hCG at next follow up visit or refer patient to obstetrical/gynecological (OB/GYN) for further evaluation Women who are breast-feeding or pregnant as evidenced by positive urine pregnancy test done within hours of first dosing Positive pregnant status confirmed by serum or urine pregnancy test Women with a positive pregnancy test. Women with a positive pregnancy test Positive pregnancy test in a female Positive serum pregnancy test Positive serum pregnancy test Positive pregnancy test for women of childbearing age Females with a positive pregnancy test. WOCBP who has a positive urine pregnancy test within hours before the first dose of study treatment The subject is pregnant, as defined by a presumptive sign of pregnancy such as missed menses or a positive pregnancy test DONOR: Females with a positive pregnancy test Females who are pregnant, breastfeeding or who have a positive pregnancy test at screening or Day Females who are pregnant, breastfeeding or who have a positive pregnancy test at screening or Day . Women who are breastfeeding or pregnant as evidenced by positive serum pregnancy test Known pregnancy, nursing women or positive pregnancy test Women who are breastfeeding or pregnant as evidenced by positive serum pregnancy test Positive pregnancy test in a female Positive pregnancy test Women who are breast feeding or pregnant as evidenced by positive serum pregnancy test. A WOCBP who has a positive urine pregnancy test within hours before the first dose of study treatment Pregnant (positive pregnancy test) Women with a positive pregnancy test Women with a positive pregnancy test Positive pregnancy test in women of childbearing potential Female patients who are lactating or have a positive serum pregnancy test within hours of initiation of treatment, or a positive urine pregnancy test on day before first dose of study drug, if applicable; pregnancy testing is not required for postmenopausal or surgically sterilized women Positive pregnancy test. Woman who is pregnant or lactating or has a positive pregnancy test at screening. If a woman has a positive pregnancy test, further evaluation may be conducted to rule out ongoing pregnancy to allow the patient to be eligible. Pregnant (positive pregnancy test) or lactating Women who are pregnant (confirmed by positive pregnancy test) or lactating Female subjects who have positive serum pregnancy test taken within days of study treatment Women with a positive pregnancy test at study entry. Pregnancy confirmed by pregnancy test / Lactating women; Currently pregnant (assessed by serum pregnancy test) Not pregnant (confirmed by a pregnancy test) Pregnant or breastfeeding women; positive pregnancy test within days of starting treatment Patients who are pregnant or breastfeeding; patients will be asked about the possibility of pregnancy; a pregnancy test will be obtained for those patients who have been sexually active without using birth control since their last menstrual period; pregnancy status can be confirmed using any of the following: pregnancy test, prior hysterectomy, tubal ligation, use of intra-uterine device (IUD) or Depo-Provera, or if the woman is beyond childbearing age Subject is pregnant (documented by a positive pregnancy test according to hospital standard practices) or is actively breast-feeding. Positive pregnancy test on day of surgery Positive pregnancy test or breastfeeding of patient or donor (women of childbearing age only) Positive pregnancy test Positive pregnancy test (women of childbearing age only) Positive pregnancy test or nursing (women of childbearing age only) Positive pregnancy test Pregnancy, or positive pregnancy test Currently known to be pregnant; (Note that urine pregnancy tests will be performed prior to the DXA and pQCT studies; positive pregnancy test at that time would preclude participation; a positive pregnancy test will be immediately reported to the patients primary oncology provider) Positive serum pregnancy test in WOCBP Breastfeeding women or females of childbearing potential with a positive pregnancy test prior to the procedure or the intent to become pregnant during the study. Positive pregnancy test Positive serum pregnancy test for females Pregnant or lactating; women of childbearing potential with either a positive or no pregnancy test at baseline are excluded Females who are pregnant as confirmed by a positive serum or urine pregnancy test or are breastfeeding. Positive Hemoglobin-Solubility (e.g., SickleDex or equivalent) test. Pregnancy, or positive pregnancy test