Willing to perform at least two methods of contraception Willing to use contraception throughout the study period. Willing to use adequate contraception for the duration of time on the study and for months after the last therapy Willing to use adequate contraception while on the study and until days after the last dose of study drug Willing to use adequate contraception while on the study and until days after the last dose of study drug Willing to use adequate contraception throughout the study and for weeks after study drug discontinuation Men and women must be willing to use appropriate contraception throughout study and for months after Willing to use contraception when appropriate Willing to use effective contraception for at least -days post study drug administration. Must be willing to implement contraception throughout study and for days after receiving the study drug. Must be willing to implement contraception throughout study and for the weeks following last viral administration Contraception. Women of childbearing potential must be willing to implement adequate contraception during the study. An adequate method of contraception will be at the investigator's discretion. Men must be willing to use appropriate contraception throughout study and for months after; women must be willing to use appropriate contraception throughout study and for months after Must be willing to use contraception during the study, and for days following the last dose of study drug Willing to abstain from sexual intercourse or to use an effective form of contraception during the study and for days following the last dose of MM- Must be willing to implement contraception throughout study and for the weeks following last study drug administration. Men not willing to use an effective contraception method while on study Not willing to use contraception (inclusive of abstinence) Is the subject willing to use condoms for contraception for months after receiving Toca or until there is no evidence of the virus in his/her blood, whichever is longer. If the subject is a fertile female, is she willing to use contraception for at least months? Willing to abstain from sexual intercourse or to use an effective form of contraception during the study and for days following the last dose of MM- Pregnant and lactating females, and unwillingness to use contraception; or male subject not willing to use contraception during and for days after the last dose of pazopanib therapy Willing to use adequate contraception to avoid pregnancy or impregnation until weeks after discontinuing study agent Willingness to use adequate contraception to avoid pregnancy or impregnation until weeks after discontinuing study agent Willing to continue on the same or similar type of contraception during the month course of study; if using non-hormonal contraception, continue that and if hormonal contraception continue that; if heterosexually active, must be agreeable to use some form of contraception during the trial unless husband or partner has had a vasectomy or subject has had uterus removed; safety of SDG during pregnancy has not been documented Use of adequate contraception during the study TREATMENT GROUP: Willing to avoid oral contraception use (which is not recommended while on tamoxifen treatment) for the duration of the study participation Willing to use contraception during and for month after completion of the study Willing to abstain from procreative sex or partake in appropriate form of contraception; for the purpose of this study, condom use or abstinence will be required Willing to use adequate contraception if applicable, and to continue use for weeks post last dose of GSK