Current or past participation in a study of an investigational agent or using an investigational device within four weeks of registration for protocol therapy Current or planned participation in a study of an investigational agent or using an investigational device Participation in a study of an investigational agent or device within weeks of Day Current or planned participation in a study of another investigational agent or using an investigational device. Planned participation in another study of an investigational agent or investigational device or planned use of any other agent or therapeutic device intended for therapy of glioma Current or planned participation in a study of an investigational agent or using an investigational device Current or planned participation in a study of an investigational agent or using an investigational device Current participation in or previous participation in a study of an investigational agent or using an investigational device within weeks of the first dose of study treatment Current participation in another clinical study of an investigational agent, vaccine, or device. Concomitant participation in observational studies is acceptable after sponsor approval. Participation in any other investigational drug trial or exposure to other investigational agent, device or procedure within days Current or planned participation in a study of an investigational agent or using an investigational device Participation in an investigational research study using an investigational agent within days of screening Participation in concurrent study of an investigational agent or device. Current enrollment in an investigational drug or device study, or participation in such a study within days of first administration of the hormonal agent Planned participation in another study of an investigational agent or investigational device or use of a therapeutic device intended for therapy of glioma